Apr
01
2006

Sleep Medication Unlocks Eating Disorder

By | Health, Prevention

A sleep disorder may drive people to use sleeping pills on a regular basis. Even though all efforts are made to minimize harmful side effects, emerging medical case studies are uncovering disturbing findings with the use of the sleeping pill Ambien (zolpidem). While many users report no incident with the use of this medication, others are developing a sleep-related eating disorder. They rummage through their fridges and indiscriminately consume calories ranging into the thousands. The night eaters have no recollection of their nocturnal foraging, but thy will find telltale signs of food leftovers and snacks on counters and even in their beds. Dr. Mark Mahowald, director of the Minnesota Regional Sleep Disorders Center in Minneapolis is one of the sleep experts researching the problem. He and his team are not the only ones. Researchers at the Mayo Clinic in Rochester, Minn. have made similar findings. Sanofi-Adventis, the French company that makes the drug, has defended its safety in 13 years of use in the U.S. A company spokesperson however has conceded that the package insert for Ambien carries a warning about a sleep-related eating disorder that could occur. Several sleep specialist and a number of patients tell a more specific story. Sleep-eating is one of the varieties of unusual reactions to the drug. Other reactions range from fairly benign incidents of sleepwalking to hallucinations, violent outbursts, and the most troubling one of all driving while asleep.

Sleep Medication Unlocks Eating Disorder

Sleep Medication Unlocks Eating Disorder

Dr. Carlos H. Schenck, a sleep disorders expert in Minneapolis believes that two basic instincts, sleeping and eating, become linked and two instinctive behaviors become intertwined in the sleep stage.

More about eating disorders: http://nethealthbook.com/mental-illness-mental-disorders/eating-disorders/

Reference: NY Time Digest, Tuesday, March14, 2006, page 5

Last edited Oct. 30, 2014

Dec
01
2005

Jetlag Helped By Bright Lights and Melatonin

By | Health, Prevention

The effects of long distance travel can be unpleasant: once several time zones are crossed, people are struggling to adjust to a different wake-sleep pattern, and what is know as the “circadian rhythm” has to readjust.
Eating light meals, avoiding alcohol during travel and drinking plenty of water are the suggestions, which are frequently heard. The other suggestion for travelers is adjusting their sleep times before the trip, namely going to sleep one hour earlier for each hour of time difference when traveling east. This method alone is not always practical, especially when a sudden trip with time differences of more than 8 hours are involved.
Previous research has also shown that light box therapy works and that melatonin is a useful tool in people with jet lag.
Dr. Charmane Eastman (PhD) from Rush University Medical Center has authored a study that shows that light therapy in combination with melatonin works better than light therapy alone. Dr Eastman and colleagues studied 44 healthy adults who were divided into three groups. The first group received placebo (meaning” fake” pills), the second group took 0.5 mg melatonin, and the third group received 3.0 mg melatonin. All three groups were given three days of advancing sleep-dark period with a wake time one hour earlier each morning. They also got bright light on awakening, namely four 30-minute bright-light pulses alternating with 30 minutes of room light. There were significantly larger phase advancements with 0.5 mg or 3.0 mg of melatonin, as opposed to placebo. A slightly larger shift was obtained with the 3.0 mg dose of melatonin as compared to 0.5 mg, but this difference was too small to be statistically significant.
Jetlag Helped By Bright Lights and Melatonin

Jetlag Helped By Bright Lights and Melatonin

The researchers concluded, that afternoon melatonin, morning intermittent bright lights and a gradually advancing sleep schedule was able to advance the circadian rhythm almost an hour a day. It was also found, that the lower dose of melatonin would be adequate, and as melatonin is pretty harmless compared to most drugs prescribed, people should not be afraid to use it (even the higher dose) to cope with jet lag.

Reference: The Medical Post, November 22, 2005, page 49

Last edited December 6, 2012

Jul
01
2004

Insomnia Sufferers Will Get Help

By | Health, Men's Health, Women’s Diseases

People with chronic insomnia not only have difficulties to get a good rest at night. If they reach for the currently available sleeping medications, their days start with a drug-induced mild “hangover”: they feel drowsy for a few hours, and once they discontinue the medication, withdrawal can be a problem.

A new medication by the name of indiplon to treat chronic insomnia will be a safer, more effective form of medicine for patients with sleep disorders, reports Dr. James Walsh (PhD). He is an executive director and senior scientist at St. Luke’s Hospital and the Unity Sleep Medicine Center in St. Louis. Dr. Walsh reports that the new medication has a very short half-life, meaning, that it is out of the body, by the time the patient wakes up in the morning. A 35-day trial showed that it is not only safe and effective, but also suitable to treat patients who have trouble falling asleep and those who have trouble sleeping through the night.
More studies are needed, before the medication will be available in the U.S. (conditional approved in 2007 in the US, see link above) and in Canada. Here is a more extensive review regarding this complex new sleeping pill.

Reference: The Medical Post, May 25, 2004, pg. 16

Insomnia Sufferers Will Get Help

Insomnia Sufferers Will Get Help

Comment on Nov. 5, 2012: It appears that there are problems with long-term safety studies that were never completed. I would suggest to stick to over-the-counter melatonine proparations in the 1 mg to 3 mg range. Melatonine is safe as it is a body hormone. Prescription hypnotics (as sleeping pills are called) are problematic as they do not fit into the body chemistry receptor-wise. No problems there with melatonine.

Last edited December 8, 2012