• Immunotherapy for Cancer

    Immunotherapy for Cancer

    Dr. Joseph Maroon discussed immunotherapy for cancer at the Anti-Aging Conference in Las Vegas, which I attended. He was one of the keynote speakers Dec. 14, 2024. He was a neurosurgeon in the past and has given many lectures at these yearly Anti-Aging Conferences before. The full title of his presentation was … [Read More...]

  • Treatment of Hormone Deficiencies with Bioidentical Hormones

    Treatment of Hormone Deficiencies with Bioidentical Hormones

    Dr. Thierry Hertoghe discussed treatment of hormone deficiencies with bioidentical hormones at the Anti-Aging Conference in Las Vegas, which I attended. He was one of the keynote speakers Dec. 13, 2024. He is a well-known endocrinologist from Brussels/Belgium and has given many lectures at these yearly Anti-Aging … [Read More...]

  • Menopause Revisited

    Menopause Revisited

    At the 32nd Anti-aging Conference in Las Vegas menopause was reviewed, which I call “menopause revisited”. The presenter was Dr. Sara Gottfried who is the director of Precision Medicine. She is also affiliated with the Marcus Institute of Integrative Health, Thomas Jefferson University, Philadelphia, Pennsylvania, … [Read More...]

  • Anti-Inflammatory Diets Improve Inflammation

    Anti-Inflammatory Diets Improve Inflammation

    A CNN review article noted that anti-inflammatory diets improve inflammation. This is important for medical conditions that also have inflammation attached to it. For instance, rheumatoid arthritis, diabetes or chronic kidney disease all carry inflammation with them. But according to a 2019 study more than 50% of … [Read More...]

  • Ultraprocessed Food Leads to Premature Aging

    Ultraprocessed Food Leads to Premature Aging

    An article in the medical journal “Medical News Today” found that ultraprocessed food leads to premature aging. What are ultraprocessed foods? The NOVA Food Classification System explains what ultraprocessed foods (UPFs) are and what other ones are not. Examples of ultraprocessed foods are: fatty, sweet, savory … [Read More...]

  • Vital Information about Cholesterol Drugs

    Vital Information about Cholesterol Drugs

    Most people know about statins to treat high cholesterol, but they do not have vital information about cholesterol drugs. Recently an article appeared in CNN, which was very informative. In the following I will review what is new about cholesterol lowering drugs. PCSK9 inhibitors, which are monoclonal … [Read More...]

    Aug
    01
    2005

    Tight Blood Sugar Control In Diabetics Cuts Heart Disease

    Successful treatment of type 1 diabetes in the past usually meant compliance in taking insulin shots and paying attention to a diabetic diet. Since the arrival of specific lab tests like the HbA1c levels, patient education has become more sophisticated: it is not enough to just be on shots, eat sensibly and otherwise hope for the best. As a result, it is a must for patients to monitor their glucose levels closely.
    Research that was presented at the American Diabetes Association during the 65th annual scientific session spelled out the benefits very clearly: strict control of glucose levels helps patients with type 1 diabetes to decrease the risk of stroke and cardiovascular disease by 57%!

    It has been known that tight glucose control helped to reduce diabetic nephropathy (kidney disease) and diabetic retinopathy (eye disease) in diabetics, but this is the first time that controlling glucose levels has been associated with cardiovascular disease, reports the main investigator, Dr.David Nathan from, director of the diabetes center at Massachusetts General Hospital in Boston. He also reported that every 1% reduction in HbA1c (glycosated hemoglobin) correlated with a 20% reduction in cardiovascular risk for the diabetes type 1 patient.

    These findings are significant, as the risk reduction is larger than seen in any other trials, like administering medication (statins) or placing stents.

    Tight Blood Sugar Control In Diabetics Cuts Heart Disease

    Tight Blood Sugar Control In Diabetics Cuts Heart Disease

    A similar risk reduction may also occur in patients with type 2 diabetes, but at this point no specific research on this group is available. In the meantime it is of great importance to any patient with type 1 diabetes.

    More information about:

    1. Diabetes treatment: http://nethealthbook.com/hormones/diabetes/type-2-diabetes/treatment-type-2-diabetes/

    2. Heart attacks: http://nethealthbook.com/cardiovascular-disease/heart-disease/heart-attack-myocardial-infarction-or-mi/

    Reference: The Medical Post, July 5,2005,page1, 58.

    Last edited October 29, 2014

    Aug
    01
    2005

    New Drug Reverses Macular Degeneration

    Age-related macular degeneration in the past meant blindness for the patient. In more recent years laser surgery could be a sight saver, but it also meant a more invasive treatment.
    The arrival of new anti-angiogenic drugs that can reverse age-related macular degeneration has received a lot of attention at the recent Schepens International Society ophthalmology meeting. The new drugs Macugen (pegaptanib sodium injection) and Lucentis (ranibizumab) were showing that they stopped the disease in 95% of cases. They were injected into the vitreous of the eye, and the vision of those patients who took it, actually improved.
    Macugen has been approved by Health Canada and will be launched for use in September 2005, according to Pfizer, the company behind the drug therapy.
    The research goes back to the 1970’s with the discovery of a process that forms new blood vessels in the body allowing tumors to thrive and metastasize. This research revolutionized the understanding of cancer. The new anti-angiogenic drugs fight a protein that induces angiotensin and is responsible for the abnormal blood vessel growth under the retina. This blood vessel growth causes macular degeneration (the wet form).

    New Drug Reverses Macular Degeneration

    New Drug Reverses Macular Degeneration

    Dr. Judah Folkman, a Harvard professor of cell biology, gave the presentation and he stated that this new approach would be “a lot of hope to patients.”

    More information about macular degeneration: http://nethealthbook.com/eye-diseases-and-eye-related-topics/retinal-problems/macular-degeneration/

    Reference: The Medical Post, July 5, 2005, page1, 58

    Last edited October 29, 2014

    Jul
    01
    2005

    Tooth Implants For Better Health

    Missing teeth are often just ignored -why bother? There are still all the others around to assume the necessary functions! The truth is different: missing teeth can affect us in the way we eat, speak, rest, and appear. They can influence our behavior and overall functioning. A missing tooth can also compromise the dental health of its neighbor.
    In the past the only options for missing teeth was either dental bridges or dentures. Bridges and dentures still have their place now, but the benefits for dental implants are significant.
    -They help to preserve remaining natural bone structure.
    -They reduce the need to cut out adjacent teeth for a bridge.
    -They eliminate the need for removable partials or dentures and the sores that may go along with them.
    -The roof of the mouth does not need to be covered by removable partials or complete dentures.
    -They look, feel and work just like natural teeth.
    -They support face shape, smile and provide confidence when eating and speaking.
    -A few exceptions apply: people who smoke and people who have diabetes, particularly when uncontrolled and severe, have much less success with implants, as healing is impaired. However, you may consider quitting smoking and diabetes may be able to be controlled better with the help of a specialist. Other patients who have pacemakers, artificial heart valve replacements or other implanted devices may have to stay away from implants and they may have to stick to more conventional methods such as bridges and dentures.
    The dentist will do a thorough examination to decide, whether you are a candidate for dental implants. Each tooth will be examined and a medical and dental history will be taken. Special x-rays (panoramic and tomograms) are needed to determine whether there is enough bone available. This helps to decide whether the implants can be placed directly, or whether grafting more bone will be necessary. This step is very important. It also helps the dentist to identify important structures, like nerves, sinuses and adjacent tooth roots. You will discuss all the treatment options with your dentist, which also helps to clarify expectations about the final results. This comprehensive treatment plan can be compared to building the foundation of a house. The foundation has to be solid, so the final structure holds up. A properly done dental implant should be a one-time job.

    Tooth Implants For Better Health

    Tooth Implants For Better Health

    The procedure itself is done in the dental office or in a surgical suite under a local anesthetic, and over-the-counter pain medication may be needed after the surgery. The time it takes to heal can be variable. It may take up to six months, but it is important that healthy bone develop around your implant, which is the strong bond that is needed to hold the implant in place. Once the healing is complete, your dentist takes a final impression, which is needed by the dental laboratory to create the permanent teeth.
    Once the permanent teeth are placed you will receive care and a dental hygienist will instruct you in dental hygiene. Special plastic cleaning instruments are used to avoid scratching the titanium surface of the implant. Just as with natural teeth, implant-retained teeth need to be cleaned daily and need to be regularly checked by a dentist.
    Looking at the overall picture it is clear, that the dental health and function of our teeth closely relates to every facet of our overall health, from speech to the function of our digestive tract and proper nutritional status, which affects cardiovascular health as well. A tooth implant involves a lot of detail work and effort, but its benefits are far reaching.

    Reference: Family Health, Vol. 21, No.2, Summer 2005 (June), page 9-13; published by The College of Family Physicians of Canada

    Other links re dental implants:

    Association of Prosthodontists of Canada

    American College of Prosthodontists

    Last edited December 7, 2012

    Jul
    01
    2005

    Less Alcohol And Fat, More Exercise Battles Cancer

    A lot has been said about choosing a healthy lifestyle in the prevention of cancers, but there is even better news now. It is not too late to make a switch to healthy living for those who have been diagnosed with cancer to reap significant benefits.
    Dr. Bruce Johnson, director of the Lowe Center for Thoracic Oncology at the Dana-Farber Cancer Institute says that it is helpful to impress on cancer patients to cut down on fat and to exercise more in order to reduce their risk for recurrence. Dr. Jeffrey Meyerhardt, an assistant professor of medicine at Harvard Medical School, also points out that in the past studies have shown that physical activity can lower the risk of developing colon cancer, but his new research is the first to suggest a benefit for people who already have the disease. A study including 832 patients with Stage III colon cancer who had been treated with surgery and chemotherapy showed that the cancer survival rate (where no disase was present) was 49% higher in those who were moderately active. The activity was either a two to three mph walk, six days a week, or other equivalents: running fast two times a week, or playing tennis three times a week.

    Less Alcohol And Fat, More Exercise Battles Cancer

    Less Alcohol And Fat, More Exercise Battles Cancer

    In a second study breast cancer was investigated in a group of patients who adopted a low-fat diet. Compared to those who continued to eat their regular food they were about one-fourth less likely to suffer a breast cancer recurrence in the next five years. This report comes from Dr. Rowan Chlebowski at the Harbor-UCLA Medical Center in Los Angeles. This was a larger study involving 2,437 women ages 48 to 79 years. The goal was to reduce fat intake to 20% or less of daily calories. The women were not taught to reduce total calories; just fat was reduced: no butter, margarine or baked goods. By five years, less than 10% of women on the low-fat diet had a breast cancer recurrence, compared with more than 12% of those on their usual diet. This translates into a relative risk reduction of 24%, concludes Dr. Chlebowski.

    Breast Cancer Risk From Longterm Daily Alcohol Consumption As Compared To Non-Drinkers

    Breast Cancer from Daily Exposures to Increasing Amounts Consumed

    Breast Cancer from Daily Exposures to Increasing Amounts Consumed

    Research about alcohol intake and the risk of developing breast cancer is especially important for women.The study comes also from the Dana-Farber Cancer Institute in Boston. Dr. Wendy Chen, a medical oncologist, reports that the more alcohol consumed regularly, the greater the risk. A study involved 121,700 registered nurses who were 30 to 55 years old in 1976. This study went on for 14 years and between 1980 and 1990 alcohol consumption questions were asked on several occasions; the women were followed up until 2004. Women who drank 5 to 9.9 grams of alcohol per day on average (the equivalent of a half-glass of wine) were 6% more likely to develop breast cancer than teetotalers. Women who consumed 10 to 19.9 grams per day saw their risk increase to 21%, and those who drank more than 20g per day, which means two drinks per day, were 37 % more likely to develop breast cancer. The finding of increased breast cancer rates was an independent risk factor associated solely with alcohol consumption. There has been a lot of hoopla lately about the benefits of a glass of wine for heart health, and the phrase of “everything in moderation” consoles us that a little bit cannot hurt. It turns out, that a little bit on a daily basis, alcohol in this case, can be a risky choice for women (see dose-response curve in the graph above). A link has been established between alcohol and breast cancer.

    More information on:

    Cancer causes: http://nethealthbook.com/cancer-overview/overview/epidemiology-cancer-origin-reason-cancer/

    Exercise: http://nethealthbook.com/health-nutrition-and-fitness/fitness/

    Lowering fat intake: http://nethealthbook.com/health-nutrition-and-fitness/nutrition/fat-good-bad-fatty-acids/

    Reference: The Medical Post, June7, 2005, page 20

    Last edited October 28, 2014

    Jul
    01
    2005

    Acetaminophen And Pets Aggravate Asthma

    People with respiratory problems should be cautious in their use of acetaminophen. These are the results of a large cross-sectional study from Great Britain. In the latest piece of mounting evidence British researchers pointed out that people who take acetaminophen regularly are at a higher risk of developing asthma. There are new indications that the drug may worsen respiratory disease and is also linked to COPD (chronic obstructive pulmonary disease).
    The study used previously collected data from nearly 13,500 people and was published in the American Journal of Respiratory and Critical Care. It demonstrated that daily users of acetaminophen are more likely to report asthma (odds ratio=1.81) and COPD (odds ratio=1.94) than patients who say that they never used acetaminophen. The study also investigated the relationship between respiratory illness and ASA as well as ibuprofen. Neither of the two seemed to be significantly related to the incidence of respiratory illness. The team of authors led by Dr. Tricia McKeever of the University of Nottingham did spirometry (lung function tests) and found that daily acetaminophen users had an impaired lung function of a 54 ml lower forced expiratory volume per second (FEV1). Ibuprofen users taking the medication between 1 and 5 times a month showed improvement of a 20 ml increase in FEV1. The benefit did not appear in non-users and those who took the medication on a daily basis.

    Acetaminophen And Pets Aggravate Asthma

    Acetaminophen And Pets Aggravate Asthma

    The researchers strongly recommend that patients with respiratory disease should consult with a physician and consider carefully, whether or not to take acetaminophen.
    Helping asthmatics to breathe easier has also been the subject of Japanese research. In a small prospective study Japanese researchers compared the need for inhaled corticosteroids between two groups of patients with allergic asthma. One group found new homes for the pets they were allergic to; the other opted to keep the animal at home. At the end of the 15-month average follow-up none of those who removed the pet were taking daily corticosteroids. Opposed to the first group, all but one of the patients who continued to live with their cat, dog, hamster or ferret were on daily corticosteroid treatment ranging from 200 mcg to 1600 mcg per day. Many asthma patients with animal allergies refuse to part with furry friends, but those who can fare better with less medication.

    More info on asthma: http://nethealthbook.com/lung-disease/asthma-introduction/

    Reference: The Medical Post, May 31, 2005, page 49 and 50

    Last edited October 28, 2014

    Jul
    01
    2005

    Power Lines And Childhood Leukemia

    High voltage power lines have come under scrutiny in the past, and researchers have examined health risks, especially the cancer risk. Several reports exist that either contradict or support that the magnetic fields associated with power lines can cause cancer. There have been publications that pointed out a link to childhood leukemia, and new research has re-examined the link between childhood leukemia and high voltage power lines.
    Under the leadership of Dr. Gerald J. Draper from the University of Oxford new studies have been made available and published in the British Medical Journal. The researchers examined the population living within 1 km from 275 to 400 kV power lines. Dr. Draper’s group found no association between the distance from power lines and the overall incidence of cancer.

    One finding however was different: children who lived within 200 m of high voltage power lines had a relative risk for leukemia of 1.69-fold as compared to those who lived 600 m away, who had no elevated risk. The relative risk for those living 200 to 600 m away from the lines was still elevated at 1.23-fold (where 1-fold is no risk). The research group points out that the increased risk cannot only be explained by the presence of magnetic fields, and some of the reasons are at this point unknown. Dr. Heather O. Dickinson from the University of Newcastle upon Tyne writes in an accompanying editorial that the magnetic fields surrounding the power lines amount to “about 1% of the earth’s magnetic field, which affects all of us at all times.”

    Power Lines And Childhood Leukemia

    Power Lines And Childhood Leukemia

    According to Dr. Draper’s research there are only 5 cases of childhood leukemia per year associated with the presence of power lines, and researchers agree that there is a link, however it remains a weak one.

    More information about leukemia: http://nethealthbook.com/cancer-overview/leukemia/leukemia-acute-leukemia/childhood-leukemia/

    Reference: BMJ 2005:330:1279-1280,1290-1293

    Last edited October 28, 2014

    Jul
    01
    2005

    Diet Can Influence Acne

    The old dermatological dogma that diet can play a role in the development of acne has been tossed back and forth. Some parties agree, others disagree. An old study by Fulton et al., which goes back to 1969, claims that patients who ate chocolate bars were compared to those who ate”pseudo-chocolate”, and no difference was found between the two groups. Both had the same amount of acne lesions. Critics of this poorly designed study however point out, that the” fake chocolate” contained just as much sugar and just as much trans fat as real chocolate. Trans fats are also known to contribute to inflammation, a condition that is present in acne.
    In the meantime a 2002 study that was published in the Archives of Dermatology has taken a closer look at acne. Researchers took a look at islanders from Papua, New Guinea, and the Ache people of Paraguay. Both groups eat a non-Western low-glycemic diet. 1315 subjects were checked, and not a single case of acne was found. Even though this is merely an observational study, the results are impressive. Similar results have been reported in Okinawans, the South African Bantus, the Zulu and the Inuit. Even though these groups are continents apart, the common denominator is the same. Each group eats a non-Western diet. Another publication in 2005 in the Journal of the American Academy of Dermatology evaluated data from the Nurses Health Study II for a link between teenage acne and milk intake, and there was indeed a positive association. It may be that a milk allergy could be the explanation. Further evaluation is needed to pinpoint, which active compounds in milk are the culprits.

    Diet Can Influence Acne

    Diet Can Influence Acne

    For now research points out that hyperinsulinemia, a metabolic condition stemming from an overload of highly refined and high glycemic carbohydrate foods, and its related hormonal cascade is the crucial link between the Western diet and acne. Other factors may emerge from investigating how milk consumption worsens acne.

    More info on acne: http://nethealthbook.com/dermatology-skin-disease/acne-vulgaris/

    Reference: The Medical Post, May 31, 2005, page 29

    Last edited October 28, 2014

    Jun
    01
    2005

    Pancreatic Cancer And Processed Meats

    A large multi-ethnic study analyzed data from 190,545 men and women at the Cancer Research Center at the University of Hawaii. In an average follow-up time of 7 years there were 482 incidents of pancreatic cancer, and it became obvious that processed meats play a role in the increase of pancreatic cancer. After taking other risk factors into consideration like a positive family history, age, smoking and diabetes mellitus, those patients who consumed the largest amount of processed meats had a 67% increased risk for pancreatic cancer as opposed to those who had the lowest intake of these foods. A diet rich in red meats increased the risk by about 50%.

    Poultry, fish, dairy products and egg intake showed no pancreatic cancer risk factor, nor did it matter how much fat, saturated fat or cholesterol was consumed over the 7 year observation period.

    The lead investigator of the study, Dr. Ute Noethlings, observes that the risk increase is a consequence of the meat preparation with carcinogens. The main culprit would very likely be sodium nitrite, which is a preservative that also enhances the meat color.

    Pancreatic Cancer And Processed Meats

    Pancreatic Cancer And Processed Meats

    For the consumer it means taking a critical look at processed meats before picking up sausages with your next shopping. Read the labels, avoid sodium nitrite. Your pancreas will thank you for it!

    More information on pancreatic cancer: http://nethealthbook.com/cancer-overview/pancreatic-cancer-pancreas-cancer-or-cancer-of-the-pancreas/

    Reference: The Medical Post, May 17, 2005, page 50

    Last edited October 28, 2014

    Jun
    01
    2005

    Mixing Medications With Herbs Spells Trouble

    It is generally accepted that prescription medications may have side effects, and there is also the belief that herbal medicines are more desirable, as they cannot possibly have dangerous side effects.
    An anonymous survey of rheumatology patients in the United Kingdom shed some light into the use of over-the-counter herbal remedies: nearly half of the patients (40%) had used herbal remedies in the past six month in the hope of enhancing their health. Trouble started for one in ten patients who took an herbal remedy that could negatively interfere with their traditional medicines. Dr. Wendy Holden of the Nuffield Orthopedic Center in Oxford, the author of this study, reported that the risk is especially high for rheumatology patients who take anti-inflammatory drugs in combination with herbs. The traditional medicines do have a risk for gastrointestinal bleeding, however the additions of herbs like ginkgo biloba, ginger, devil’s claw and even garlic can increase the anticoagulant effect and bleeding may be the consequence. Some patients who reported the use of Echinacea were increasing the risk of a liver disease. Of those patients who took a potentially harmful treatment combination 92% were unaware of the risk. Less than half had mentioned to their physicians that they used herbal medications in combination with their prescription medications.

    Mixing Medications With Herbs Spells Trouble

    Mixing Medications With Herbs Spells Trouble

    Herbal medicines are powerful and their effects and side effects have to be taken into consideration. It is important for the patient to mention every medication, even the seemingly harmless over-the-counter herbal remedies, to the treating physician, as the mix may be not a winning combination, but one that is hazardous.

    Reference: The Medical Post, May 10, 2005, page 8

    Last edited December 12, 2012

    Jun
    01
    2005

    Epstein-Barr Virus Responsible For Multiple Sclerosis

    Multiple Sclerosis (MS) is a chronic disease, which is dreaded by patients and a puzzle to researchers. While there are MS treatments that control the disease, it remains crucial to treat the early onset. So far the triggering factors have been an unsolved puzzle. Genetic traits and poor nutrition have been implied, yet there has been no conclusive evidence. For a long time there has been the suspicion amongst researchers, that a “multiple sclerosis virus” could be the culprit.

    New research, which has been published in the Journal of the American Medical Association shows that the truth is not far off.

    Between 1988 and 2000 blood samples have been taken in a study among medical personnel of the United States. Special attention was paid to the group that was granted a permanent disability due to chronic illness. Amongst those who had Multiple Sclerosis, positive blood tests for Epstein Barr virus titers were prominent. The affected individuals were young adults, and the infection with the Epstein-Barr virus had occurred several years before the onset of the illness (the average time between the collection of the blood specimen and the onset of MS was 4 years.) There was also a correlation between the age of the patient and the occurrence of illness. The risk at age 25 was three-fold higher than at age 20 to contract Epstein Barr viral infection. Another strong indicator was an elevated serum level of IgG antibodies to EBNA complex or EBNA-1. This finding was associated with a three-fold risk for the development of MS.

    Epstein-Barr Virus Responsible For Multiple Sclerosis

    Epstein-Barr Virus Responsible For Multiple Sclerosis

    This result would be of interest to young adults who were infected with mononucleosis, as the Epstein-Barr virus, which triggers the seemingly harmless and self-limiting “kissing disease”, seems to entail a higher risk for the development of MS in a younger adult population.

    More information on MS:  http://nethealthbook.com/neurology-neurological-disease/multiple-sclerosis/

    Reference: JAMA Vol293, Nr.20, 2496-2501, May 25,2005

    Last edited October 28, 2014