Jul
01
2007

Regular Exercise Will Delay Onset Of Alzheimer’s Or Dementia

Alzheimer’s and other types of dementia have become a disease that is dreaded by people approaching middle age. As the population ages it has made its way into the foreground not only for the ageing group but also for younger family members who will face difficult tasks as caregivers to their loved ones.

Research is dealing with a possibility of halting the disease progression, and there are encouraging signs, that more effective treatment will be available, as long as the condition is diagnosed and treated in its early stages.

It is also logical to look at preventative measures. Healthy lifestyle choices have been cited, and a closer look has been taken by Dr. Eric Larson, executive director of the Center for Health Studies of the Group Health Cooperative, Seattle. He reports that it does at this point not seem probable that Alzheimer’s dementia can always be prevented from happening, but the onset can be delayed. Four observational studies have shown with consistency, a 30% to 40% reduction in the incidence of Alzheimer’s when people get regular exercise.

In his own study Dr. Larson looked at 2581 individuals age 65 and over. They were tested for cognitive function and interviewed about their exercise habits every two years. It was found that those who followed an exercise regime 3 or four times per week had a 40 % reduction in the risk of developing dementia compared to those who exercised less than 3 times per week.

Regular Exercise Will Delay Onset Of Alzheimer’s Or Dementia

Regular Exercise Will Delay Onset Of Alzheimer’s Or Dementia

Exercise could consist of at least 15 minutes of hiking, aerobics, stretching, calisthenics, water aerobics, swimming, or weight training. It was also of interest to note that people with the lowest physical performance benefited most from the exercise. For people in the higher age bracket prevention of dementia (and other ills) does not have to be costly. A good pair of walking or running shoes (used more than 3 times per week) will pay a healthy dividend.

More information on prevention of Alzheimer’s and dementia: https://www.askdrray.com/dementia-prevented-with-diet-and-exercise/

Reference regarding the work of Dr. Larson: http://www.news-medical.net/news/2006/05/23/18087.aspx

Last edited December 18, 2014

Jul
01
2007

Waist line reduction scores in health prevention

To women waist measurement has always been of importance. Increased waist measurement and weight gain go hand in hand, and a poor fitting garment in the waist usually signals to cut out the junk food. In the past century extremely tiny waists became an unhealthy obsession, till common sense got the upper hand.

In the past males seemed to be unperturbed by a large girth and often ridiculed the opposite sex about their preoccupation with their waist lines. With more knowledge about the intricate play of metabolism increased waist circumference is a signal to health problems. It may be that a simple measuring tape can be one of the most helpful tools to predict a group of health problems in males. While type 2 diabetes, hypertension and high cholesterol and triglycerides are the problems that would first come to mind, there are more, namely coronary artery disease, prostate enlargement, a high prostate-specific antigen level, erectile dysfunction and ejaculatory dysfunction. Dr. Steven Kaplan, professor of urology at Cornell University, New York presented a study at the American Urological Association. Men with moderate to severe urinary tract symptoms were divided into groups based on their waist sizes, 30 to 36 inches, 36 to 40 inches and greater than 40 inches.

Waist line reduction scores in health prevention

Waist line reduction scores in health prevention

Results surprised even the researchers. Metabolic disorders like diabetes showed an incidence of 11.25% in the first group, 22.3 % in the next higher group and 37.8% in the group with waistlines over 40 inches. Erectile dysfunction was seen in 34.6%, 49.5% and 78.6 % respectively. The percentiles for hypertension showed 12.6% in the first group, versus 24.7% and 37.8 %. The researchers stressed that male pelvic dysfunction and the derailment of metabolic function, also known as the “metabolic syndrome” are closely linked.

More information about metabolic syndrome: http://nethealthbook.com/hormones/metabolic-syndrome/

Last edited November 2, 2014

Jul
01
2007

Incense Use Causes Cancer Of The Respiratory System

Incense use has been common in East Asia for a long time, but also in the Western world incense burning is not uncommon. It became very much “in” to burn incense sticks to create a certain “atmosphere” in a room. Incense burning during religious celebrations in some churches is a custom that goes back well over 1000 years. It is easy enough to observe, how a cloud of incense triggers a chorus of coughing and clearing of throats in a church ceremony. It has never been a laughing matter to people who suffer of allergies and asthma, as incense smoke –just like any other smoke- is a source of airway irritation.

But a bit of a cough and airway irritation are the smaller problems that long term incense use has in store. A study involving 61,320 Singapore Chinese showed that long term users had more than twice the relative risk of non-nasopharyngeal cancers of the upper respiratory tract, compared with people who did not use incense. The risk of squamous cell carcinomas of the lung rose 1.7 fold and the risk of squamous cell carcinomas of the entire respiratory tract rose 1.8-fold among long-term incense users, wrote Dr. Fribourg and his colleagues of the University of Minnesota, Minneapolis who conducted the study. The participants in the study were 45 to 75 years old and free of cancer when they enrolled in the study from 1993 to 1998. Living conditions, life style and dietary factors were examined and results were adjusted for a host of factors, such as cigarette smoking, alcohol intake, gender differences, and intake of Chinese preserved food.

Incense Use Causes Cancer Of The Respiratory System

Incense Use Causes Cancer Of The Respiratory System

The researchers also noted that incense burning is deeply engrained into the way of daily living in Southeast Asia. About half of the population burns incense at home every day. Incense smoke contains a large amount of particular matter and the burning releases many possible carcinogens including polyaromatic hydrocarbons, carbonyls and benzene.

More information regarding nose cancer: http://nethealthbook.com/ear-nose-and-throat-diseases-otolaryngology-ent/nose-problems/nose-cancer/

Reference: First published June 21, 2007 and subsequently published in a 2008 journal.

Last edited November 2, 2014

Apr
01
2007

MRI Scan Finds Hidden Cancer in Opposite Breast

Approximately 1000 women from 25 cancer centers throughout the US who were recently diagnosed with breast cancer in one breast were all examined, radio graphed with conventional mammograms. They also received an MRI scan study of the opposite breast to make sure no hidden cancer would be overlooked. To the surprise of the investigators 1 in 10 women were found to have cancer in the opposite breast that would have conventionally passed as “normal”. More than 90% of these women were picked up with an MRI scan of the opposite breast that up to now would not have been part of the routine work-up. Dr. Elias A. Zerhouni from the National Institutes of Health (NIH) said that it would be a great break through to have a new technique of diagnosing these women with early cancer in the opposite breast. By diagnosing this condition early, the cancer treatment can be customized to the exact breast cancer stage improving survival significantly for these women.Dr. Constance Lehman, the principal investigator of this ACRIN Breast MRI Trial who is also professor of radiology as well as the director of breast imaging at the University of Washington and Seattle Cancer Care Alliance, pointed out that unnecessary bilateral mastectomies (= surgical breast removal) can be avoided in the 90% women whose opposite breasts were normal. At the same time the 10% of women who were accurately diagnosed with early breast cancer can be treated early and effectively.

MRI Scan Finds Hidden Cancer in Opposite Breast

MRI Scan Finds Hidden Cancer in Opposite Breast

This trial has been started in April of 2003 and follow-up examinations were done at 12-18 and 24-30 months. This already shows that the group of 30 patients diagnosed with breast cancer in the opposite breast has a much better survival than patients would have had in the past. However, the final figures will only be available several years into the future.

The cancer specialists in the US have estimated that in 2007 there will be approximately 178,480 women who will be diagnosed with breast cancer and about 40,460 will likely die from the disease.

Reference: The New England Journal of Medicine (NEJM), Vol. 356, No.13, March 29, 2007

Last edited December 5, 2012

Mar
01
2007

Check For Vitamin B12 Deficiency In Elderly

Elderly patients frequently are seen at the doctor’s office because they are “feeling poorly”. Concerned family members mention that there is lack of energy, and mental impairment may also be present. Immediately there may be the question, whether these are symptoms of Alzheimers disease. The other observation may be that the older person is not eating properly. Family physicians will order laboratory tests including vitamin B12 levels. If a deficiency is shown, patients will be advised to take a vitamin supplement, and they may receive injections of vitamin B12.
The unfortunate fact is that vitamin B 12 levels are notoriously unreliable in the diagnosis of deficiency. As early as 1988 a publication in the New England Journal of Medicine showed that neuropsychiatric disorder due to vitamin B12 deficiency can be present in a patient who had normal blood levels and no other findings. It does take some other avenues to detect the deficiency. The blood can be tested for the metabolite called MMA (methylmalonic acid) which is raised with vitamin 12 deficiency. A second test is the measurement of HTC (holotranscobalamin), which is the fraction of vitamin B12 bound to the plasma protein transcobalamin, which delivers the vitamin to the tissues of the body.
Dr. Cherie McCracken and colleagues from the department of psychiatry at Liverpool University, England studied 42 men and 42 women ages 69 to 93.They were tested for cognitive functions like orientation, language, attention and memory. In addition researchers took measurements of the MMA and HTC, the tests mentioned above. None of the test persons had dementia due to the selection criteria, but 31% were cognitively impaired. Mental scores indicating cognitive impairment were associated with increasing age and MMA, and the areas of language comprehension, language expression and ideation practice (translating an idea into an action) were affected.

Check For Vitamin B12 Deficiency In Elderly

Check For Vitamin B12 Deficiency In Elderly

The reason for the correlation of MMA with impairment of brain function can be explained by the fact that MMA is toxic to the oxidative function of mitochondria. The process is like a chain reaction: when mitochondria are poisoned, the nerve cells will lack energy for proper function.
Despite this sophisticated interplay of blood levels and cell function in the brain, the message that comes from the researchers is very simple. The MMA has to be ordered as a test in elderly persons, and the next important step is supplementation with vitamin B12 to prevent deterioration in mental functioning.

More information about:

1. Causes of dementia: http://nethealthbook.com/neurology-neurological-disease/alzheimers-dementia-and-delirium/dementia/

2. Pernicious anemia: http://nethealthbook.com/anemia/anemia-from-deficient-red-blood-cell-production/megaloblastic-macrocytic-anemia/

Reference: The Medical Post, January 16, 2007, page 27

Last edited November 2, 2014

Mar
01
2007

Pancreatitis Can Occur With Statin Use

Drug safety is a concern in the administration of prescription medications and non- prescriptions and any new drug that hits the market has undergone a rigorous screening procedure before its release. Side effects still can occur, and all of the possible ones have to be listed. For physicians it always remains a matter of careful judgement, whether the benefits of a prescription outweigh the disadvantages of any side effects. It is also a concern for the patient to be fully informed. Despite all precautions there are still surprises: some drugs have been taken of the shelves, because the side effects showed up after some time and the risk for the patients were too much. There may be the sense of false security about a prescription drug that has been on the market for a long time that all is known about possible side effects, but researchers and physicians remain alert to the fact that there may be adverse drug reactions that have not been observed.Statins, which are used for lowering high cholesterol levels, have been researched in a review of case reports and observational studies led by Dr.Sonal Singh of Wake Forest University in Winston-Salem, N.C. The authors reported in the December issue of Drug Safety that there have been numerous case reports in which statins have been implicated in acute pancreatitis. It appears to be a genuine adverse reaction, but it remains rare. The researchers estimate that there would be one case of acute pancreatitis in 300,000 patients treated with statins for a year.

Pancreatitis Can Occur With Statin Use

Pancreatitis Can Occur With Statin Use

The review suggested that pancreatitis can occur in high and low statin doses, but it is more likely to happen after many months of therapy. Due to the low incidence and mild severity in the majority of cases, statin therapy is still considered safe.
The first line of defense in the treatment of high cholesterol remains a proper diet and an active lifestyle. Statins are needed for patients with familial hypercholesterolemia and those where diet and lifestyle choices have not been successful enough.

More information about:

1. Statins: https://www.askdrray.com/statins-can-hurt-the-consumer/

2. Pancreatitis: http://nethealthbook.com/digestive-system-and-gastrointestinal-disorders/pancreatitis/acute-pancreatitis/

Reference: The Medical Post, February 2, 2007, page 2

Last edited November 2, 2014

Mar
01
2007

Depression Increases Stroke Risk

Strokes have been observed mainly in the aging population, and various lifestyle factors play a role in the risks. It is generally well known that smoking is one of them. High blood pressure that is left untreated will have a stroke as a consequence. Even though in the past the development of a stroke was more commonly seen in older patients, it has become something to be reckoned with for patients that are middle aged.
While some risk factors are the same in all the age groups, researches scrutinized the age group under 65 for additional risk factors. The one that stands out is depression.
Margaret Kelly-Hayes Ed.D. and her colleagues evaluated data from the Framingham Heart Study, looking at 4,120 participants aged 29-100 years who were followed for 8 years. In the course of their research they checked for symptoms of depression by administering the Center for Epidemiological Studies Depression Scale (CES-D). If patients were taking medication for depression they were included in the study. In participants under 65 with depressive symptoms the stroke risk was found to be four times higher than in the population of the same age group without depressive symptoms.

The findings were commented on by Dr. Francisco Javier Carod-Artal, of the Sarah Hospital in Brasilia, Brazil. He found that a growing body of evidence suggests that biological mechanisms underlie a bidirectional link between depression and many neurological illnesses. Mood disorders can influence the development of disease.

Depression Increases Stroke Risk

Depressed patients 4 times more at risk of getting stroke

Pinpointing exactly why depressive symptoms are increasing the risk for strokes is a challenge. Dr. David Spiegel from Stanford (Cal.) University was interviewed and he believes that the problem is environmental as well as biologic. People who are depressed may smoke more, avoid social contact, may lack self care and neglect taking blood pressure medication.
In any event it is important to treat depression, and to take care of all the known steps in stroke prevention.

More information about:

1. Stroke prevention: http://nethealthbook.com/cardiovascular-disease/stroke-and-brain-aneurysm/stroke-prevention/

2. Depression: http://nethealthbook.com/mental-illness-mental-disorders/mood-disorders/depression/

Reference: MD Consult News, January 29, 2007

Last edited November 2, 2014

Feb
01
2007

Avoiding Back Pain By Relaxed Sitting

This article is about “avoiding back pain by relaxed sitting”. Notably, parents and educators often reprimand children and students to “sit up straight”. The results however are not that favorable. Truly, a 90 degree angle in this position is causing problems. Specifically, it causes the largest movement of the spinal disc and a lot of strain. To put it another way, conventional wisdom has it that sitting up straight avoids back pain. It must be remembered, this has important implications for a large population group that has work situations with mostly sitting jobs. In addition, consequences of bad posture are also quite visible: lower back pain is the leading cause of disability in the U.S. and Canada and a major cause for missed work days.

Improper posture and back pain are related

Investigators have presented evidence, that a 135 degree body/thigh sitting position, leaning back, is the optimal position to avoid back pain. The author of the study, Dr.W. Bashir from the department of radiology and diagnostic imaging at the University of Alberta Hospital in Edmonton emphasizes, that the angle of posture has been under question for some time, and improper posture and back pain are related.

Positional MRI scans 

Positional MRI scans have shed more evidence on the spine. There are special MRI machines that take images when the patient is not in a supine position, but in a position that allows the patient free motion during the test. Spinal angles can be measured and spinal disk movement can be observed in various positions and angles.
The 90 degree angle showed most spinal disk movement, creating stress for the spine. Another unfavorable position is a slouching posture.

Avoiding Back Pain By Relaxed Sitting

Avoiding Back Pain By Relaxed Sitting

Scan results showed a reduction in spinal disk height, signifying more wear and tear of the lumbar spine. Spinal disk movement was least pronounced with the 135 degree angle. This more relaxed position poses less strain on spinal disks and the associated muscles and tendons. Employees sitting comfortably versus sitting up straight can make the job place friendlier to people’s backs.

More about back pain: http://nethealthbook.com/arthritis/lower-back-pain/

Reference: The Medical Post, January 16, 2007, page17

Last edited November 2, 2014

Jan
01
2007

Ballroom Dancing Improves Heart Health

It has been pointed out that there is not such a notion “It’s too late now to think of an exercise program”.
Researchers led by Dr. Romualdo Belardinelli, director of cardiac rehabilitation from the Lancisi heart Institute in Ancona, Italy took a close look at 110 patients with stable chronic heart failure. The average age of the patients was 59 years and 89 of them were men. The group was assigned different physical activities. Forty-four patients used an exercise bike or exercise treadmill three times a week for 8 weeks. Forty- four other patients chose to participate in 21-minutes of ballroom dancing consisting of waltzes (alternating slow and fast) three times per week. A third group of 22 patients had no exercise. Heart rates during exercise training and dancing were similar at 110 respectively 113 beats per minute. Cardiopulmonary fitness improved at a similar rate in both groups. Oxygen consumption increased by 16 % in the exercise group and by 18% in the dance group. In other words, exercise fitness had significantly improved in these two groups.

Quality of life as measured by the Minnesota Living With Heart Failure Questionnaire improved significantly more in the ballroom dance group, particularly in the emotional domain.

Ballroom Dancing Improves Heart Health

Ballroom Dancing Improves Heart Health

The findings are not just of significance to patients with heart failure. It is the observation that ballroom dancing seems to be a more effective way to get people into an exercise program who otherwise would not be interested in this. For some people it is simply more enjoyable to dance and enjoy social interaction as an additional benefit than running on a treadmill.

More information is available about:

1. Fitness: http://nethealthbook.com/health-nutrition-and-fitness/fitness/

2. Health for adults: http://nethealthbook.com/health-adults/

3. Health for seniors: http://nethealthbook.com/health-seniors/

Reference: The Medical Post Dec. 19, 2006, page 17

Last edited November 2, 2014

Jan
01
2007

Acetaminophen Overdosing Hazards

The FDA has expressed some concerns about the self-medicating with acetaminophen as this can led to an acetaminophen overdose. The over-the-counter medication is commonly used and especially in the winter season many sufferers of colds or influenzas will keep it handy. It is readily available, not only in pharmacies but also in supermarkets under the generic name or under brand names such as the commonly used Tylenol. It exists in dosages for adults and there are pediatric preparations like Children’s Tylenol. Acetaminophen is also a common ingredient in cold remedies. Every vial displays a clear warning that the content is enough to cause serious harm. Dosage instructions are also clearly spelled out.
More than 200 million people take Tylenol each year and 400 people die of liver failure every year, as they have accidentally taken too much.
Dr. Charles Cain from the New York Presbyterian Hospital has cautioned that overdoses can happen relatively easy. A patient is not to exceed 4 grams of acetaminophen per day. If the pain reliever is taken every 4 hours instead of the recommended interval of 6 hours, such as 2 extra-strength Tylenol at 500 mg each and some cold medication is added to that, patients may easily reach 4-6 grams of acetaminophen per day. If this practice continues for a few days, it can lead to liver damage, because the liver cannot keep up with the elimination of the drug. Other substances metabolized by the liver such as alcohol can become a serious hazard, if they are combined with acetaminophen. The effects of alcohol slow down the elimination of Tylenol by the liver.

Acetaminophen Overdosing Hazards

Acetaminophen Overdosing Hazards

It is for this reason that it is important to observe closely how much of the medication is taken in total: if a patient is already taking Tylenol for headaches, more acetaminophen (Tylenol) in the form of an over-the-counter cold medication should not be added as  would be reached.
These medications have to be used with an eye to overall daily use and the amount used over a period of time. Used with care acetaminophen remains very safe.

Reference: December 20, 2006 online issue of Time

Last edited December 5, 2012