Jul
01
2007

Incense Use Causes Cancer Of The Respiratory System

Incense use has been common in East Asia for a long time, but also in the Western world incense burning is not uncommon. It became very much “in” to burn incense sticks to create a certain “atmosphere” in a room. Incense burning during religious celebrations in some churches is a custom that goes back well over 1000 years. It is easy enough to observe, how a cloud of incense triggers a chorus of coughing and clearing of throats in a church ceremony. It has never been a laughing matter to people who suffer of allergies and asthma, as incense smoke –just like any other smoke- is a source of airway irritation.

But a bit of a cough and airway irritation are the smaller problems that long term incense use has in store. A study involving 61,320 Singapore Chinese showed that long term users had more than twice the relative risk of non-nasopharyngeal cancers of the upper respiratory tract, compared with people who did not use incense. The risk of squamous cell carcinomas of the lung rose 1.7 fold and the risk of squamous cell carcinomas of the entire respiratory tract rose 1.8-fold among long-term incense users, wrote Dr. Fribourg and his colleagues of the University of Minnesota, Minneapolis who conducted the study. The participants in the study were 45 to 75 years old and free of cancer when they enrolled in the study from 1993 to 1998. Living conditions, life style and dietary factors were examined and results were adjusted for a host of factors, such as cigarette smoking, alcohol intake, gender differences, and intake of Chinese preserved food.

Incense Use Causes Cancer Of The Respiratory System

Incense Use Causes Cancer Of The Respiratory System

The researchers also noted that incense burning is deeply engrained into the way of daily living in Southeast Asia. About half of the population burns incense at home every day. Incense smoke contains a large amount of particular matter and the burning releases many possible carcinogens including polyaromatic hydrocarbons, carbonyls and benzene.

More information regarding nose cancer: http://nethealthbook.com/ear-nose-and-throat-diseases-otolaryngology-ent/nose-problems/nose-cancer/

Reference: First published June 21, 2007 and subsequently published in a 2008 journal.

Last edited November 2, 2014

Apr
01
2007

MRI Scan Finds Hidden Cancer in Opposite Breast

Approximately 1000 women from 25 cancer centers throughout the US who were recently diagnosed with breast cancer in one breast were all examined, radio graphed with conventional mammograms. They also received an MRI scan study of the opposite breast to make sure no hidden cancer would be overlooked. To the surprise of the investigators 1 in 10 women were found to have cancer in the opposite breast that would have conventionally passed as “normal”. More than 90% of these women were picked up with an MRI scan of the opposite breast that up to now would not have been part of the routine work-up. Dr. Elias A. Zerhouni from the National Institutes of Health (NIH) said that it would be a great break through to have a new technique of diagnosing these women with early cancer in the opposite breast. By diagnosing this condition early, the cancer treatment can be customized to the exact breast cancer stage improving survival significantly for these women.Dr. Constance Lehman, the principal investigator of this ACRIN Breast MRI Trial who is also professor of radiology as well as the director of breast imaging at the University of Washington and Seattle Cancer Care Alliance, pointed out that unnecessary bilateral mastectomies (= surgical breast removal) can be avoided in the 90% women whose opposite breasts were normal. At the same time the 10% of women who were accurately diagnosed with early breast cancer can be treated early and effectively.

MRI Scan Finds Hidden Cancer in Opposite Breast

MRI Scan Finds Hidden Cancer in Opposite Breast

This trial has been started in April of 2003 and follow-up examinations were done at 12-18 and 24-30 months. This already shows that the group of 30 patients diagnosed with breast cancer in the opposite breast has a much better survival than patients would have had in the past. However, the final figures will only be available several years into the future.

The cancer specialists in the US have estimated that in 2007 there will be approximately 178,480 women who will be diagnosed with breast cancer and about 40,460 will likely die from the disease.

Reference: The New England Journal of Medicine (NEJM), Vol. 356, No.13, March 29, 2007

Last edited December 5, 2012

Feb
01
2007

Lycopene Benefits Backed By Science

Lately a lot of attention has been directed to the health benefits of vegetables and fruit. Vitamin C has long been an accepted household term, and nobody questions the benefits. Newer buzz words are the terms “bioflavonoids” and “antioxidants”. Some products are aggressively marketed extolling the above named beneficial substances, but often the consumer is left mildly bewildered by exaggerated claims. Often the sale prices of these miracle foods are as lofty as the bold statements that go along with them.
For any shopper it is important to know that some of the most beneficial foods are not high priced items, but very common staples. Take tomatoes, for instance. They are a significant source for the substance lycopene, which lately has received a lot of attention. Lycopene and its dietary sources as well as its benefits have been researched world wide, and the results are now in. It is responsible for the red color in fruit or vegetables, such as tomatoes, and its isomeric form 5-cis-lycopene is the most stable form having the highest antioxidant properties. Common dietary sources are tomatoes, watermelons, pink guava, pink grapefruit, papaya, apricot and other fruit. In the Western diet tomato-based foods account for about 85% of dietary sources of Lycopene. Studies have shown that lycopene is more efficiently absorbed from processed tomato products compared to raw tomatoes. Once it is absorbed it is distributed throughout the body. The highest levels showed up in the testes, the adrenal glands, prostate, breast and liver.
Research going back to 1995 showed an inverse relationship between the consumption of tomatoes and the risk of prostate cancer. A follow up publication in 1999 showed that the same inverse relation of lycopene intake and cancer also included breast, cervical, ovarian, liver and other organ sites. Further studies have followed these initial publications, and the great majority of them suggest that an increased intake of lycopene showed an association with a significant reduction in the risk of many cancers.
Coronary heart disease and lycopene benefits were also examined. The strongest population based evidence comes from a multi center case control study in Europe (EURAMIC). 662 Cases and 717 controls were recruited from 10 different European countries, and there was a significant relationship between levels of lycopene in fatty tissue and the risk of myocardial infarction. Lower lycopene levels were associated with a higher risk of heart attacks.Lycopene was also shown to decrease levels of oxidized LDL (LDL or low density lipoprotein is known as the “bad” cholesterol). Another small study showed that lycopene was reducing total cholesterol levels and as a result was lowering the risk of coronary heart disease (CHD).
The list of benefits does not end here: the dietary oxidant reduces oxidative stress and levels of bone turnover markers, meaning that it may contribute to the bone health, especially reducing the risk of osteoporosis in postmenopausal women.

Lycopene Benefits Backed By Science

Lycopene Benefits Backed By Science

For people with mild hypertension (high blood pressure), consumption of lycopene resulted in significant reductions of systolic and diastolic blood pressures.
Infertility in males was significantly helped by lycopene intake. In a study infertile man received 8 mg lycopene per day in capsule form. Laboratory tests confirmed an increased sperm density along with functional sperm concentration and mobility. This treatment protocol with lycopene supplementation resulted in a success rate of 36% pregnancies in their partners.
Pregnant women with pre-eclampsia who were treated with lycopene supplement significantly improved, which was shown by decreased diastolic blood pressure, the reduction of pre-eclampsia and a decrease of intrauterine growth retardation, resulting in a healthier mother and baby.
Future research is pending surrounding lycopene in metabolic and inflammatory diseases and in its role of possibly preventing neurodegenerative diseases such as Alzheimer’s disease. Other inflammatory conditions such as arthritis and emphysema will likely also be shown to benefit from lycopene. Preliminary data has already indicated this.
The Food and Drug Administration (FDA) of USA has recently approved lycopene as a safe “natural coloring agent” and a Generally Recognized as a Safe (GRAS) component. The Department of Nutritional Sciences , Faculty of Medicine, University of Toronto, c/o Dr. A.V. Rao et al. who completed this meta analysis of the recent literature have recommended that we all consume a regular daily lycopene dose in our food and supplements as part of our diet for good health.

More info about lycopene and prostate cancer: http://nethealthbook.com/news/lycopene-reduces-prostate-cancer-risk/

Reference: The Whitehall-Robins Report, December 2006, Volume 15, No.4

Last edited November 2, 2014

Nov
01
2006

Eat Your Salad Greens, But No Spinach

Spinach has traditionally been regarded as a healthy, green leafy vegetable and a valuable source of vitamins and minerals, in particular iron. The tedious chore of cleaning the tender greens and removing soil and sand traces has been taken care of by packinghouses. As a result, the consumer could purchase ready to eat spinach in plastic bags. These greens were a welcome ingredient for spinach salads or other dishes.
Lately all spinach has been recalled from the world’s largest producer of organic produce. Natural Selection Food has recalled a total of 34 brands that were distributed nationwide, and some of which were available also in Canada. Consumers are still being warned not to eat fresh spinach from the U.S., even though there have been no reported cases of ill effects or diseases in Canada itself. Problems have surfaced in September in form of food borne illness in the U.S. The culprit seems to be contamination with E. coli 0157:H7. Food borne illness can be serious. So far there have been 109 cases of illness in the U.S. and possibly two deaths. The worst affected area so far is Wisconsin, where 29 illnesses were reported and one person died of the disease.
As a result of this alert, salad mixes that contained a variety of greens including spinach leaves have also been pulled from the shelf. It should be mentioned that washing the spinach leaves does not make it safe to consume, as the E.coli bacteria stick to the leaves.
While it seems good-bye to spinach leaves for now, it remains important to eat your greens. Researchers at University of California in Los Angeles and colleagues at Louisiana State University analyzed the salad consumption based on the intake of salad, raw vegetables and salad dressing on 9,406 women and 8,282 men. The researchers also found from their studies that daily consumption of salad and raw vegetables is not the norm in any population group and even less prevalent among African Americans.

Eat Your Salad Greens, But No Spinach

Eat Your Salad Greens, But No Spinach

There were data from lab tests on serum nutrient levels, and it showed that consumption of salads was positively associated with above-median serum micronutrient levels of folic acid, vitamin C and E, lycopene, and alpha carotene and beta carotene. All of these nutrients are important for healthy daily functioning. They are weapons that help fight infection, heart disease and cancers. The consumption of salad and raw vegetables remains the most effective strategy for increasing the intake of important nutrients.

Reference: The Medical Post, October 3, 2006, page 21

Here is a follow-up on this story: Apparently the outbreak was caused by a wild boar and by a nearby cattle field:  http://www.foodsafetynews.com/2009/09/meaningful-outbreak-7-dole-spinach-e-coli-outbreak/#.VFaWXPTF-88

More information about food safety: http://nethealthbook.com/health-nutrition-and-fitness/nutrition/food-safety/

Last edited November 2, 2014

Oct
01
2006

Good Nutrition Is Gender Specific

It is well known that various health concerns are related to the gender of a person, but there are findings that suggest that even nutrition has to be tailored to the needs of males or females.
Calcium is known to be beneficial to bone health, and while high calcium diet may protect a woman from osteoporosis, it does not have the same evidence for men. As a matter of fact, high calcium intake in males may increase their risk of prostate cancer. For the male it means that calcium should be used in moderation and vitamin D intake could help to offset some risks.
Fat choices, mostly sources of monounsaturated fats in the form of olive oil are important for both, men and women, and for both the omega-3 fatty acids that are found in fish are excellent. Men, especially those with a risk of prostate cancer, should be cautious about loading up on flaxseed and canola oil. Alpha-linolenic acid in these two oils may be a problem for the prostate.
Iron is also emphasized in healthy nutrition, but men need less than women. In the presence of an abnormal gene, excessive iron can accumulate to harmful deposits in various organs.
Social habits, for example the drinking of alcohol seem to have more grave implication to women than to men. The glass of wine that may help reduce the risk of heart attacks and certain strokes may seem harmless enough, and average men don’t seem to develop health problems, as long as the alcohol intake is low. Larger amounts will increase the risk of many ills for males and females alike, but even low doses of alcohol may increase a woman’s risk of breast cancer.
“Super Foods” have made headlines, and all of them are known because of their high content in antioxidants. A recent study from the University of Oslo, Norway, under Dr. Bente Halverson examined, which of them are ranking highest. At the top are, in the order of strength: blackberries, grape juice from Concord grapes, artichoke hearts, walnuts and strawberries. The researchers came up with a list of high oxidant foods on the basis of typical serving sizes.

Good Nutrition Is Gender Specific

Everybody needs to find healthy food

These are the winners among the super foods and spices: blackberries, walnuts, strawberries, artichokes, cranberries, brewed coffee, raspberries, pecans, blueberries, ground cloves, grape juice and unsweetened baking chocolate. Males as well as females of all age groups will benefit from those.
Dr H. Simon, associate professor of medicine at Harvard Medical School points out that there are fundamental facts in nutrition that apply to everyone. But there is also a fine print, which varies according to gender, age and medical conditions.

More information about nutrition: http://nethealthbook.com/health-nutrition-and-fitness/nutrition/

Reference: The Medical Post, September 19, 2006, page 25

Last edited November 1, 2014

Oct
01
2006

Successful Gene Therapy For Melanoma

Scientists at the National Cancer Institute in Bethesda, Md. have developed a modality of gene therapy to treat patients with melanoma.
The therapy alters the patients’ own lymphocytes to recognize and attack cancer cells. Dr. Steven Rosenberg and his team developed the new technique by drawing a blood sample containing normal lymphocytes from an advanced melanoma patient. Next the cells are infected with a retrovirus, which delivers genes that target specific receptors on T cells. Once the cells are infused back into the patient, these receptors attach themselves to the molecules on tumor cells and activate the lymphocytes to destroy the cancer cells. This method is called “adoptive cell transfer”. In early experiments there seemed to be little or no benefit, but researchers refined the methods and found valuable and promising aspects regarding the treatment of melanoma patients. It is crucial to administer the cells in their most active growth phase. This was shown in a group of 14 patients, where 2 terminal melanoma patients experienced cancer regression. Dr. Jeffrey Medin, head of the clinical research program in gene therapy at the Ontario Cancer Institute in Toronto agrees that this new therapy is a breakthrough as it has virtually brought terminal patients “back from the brink”. It is also exciting to see that the researchers could refine the techniques in order to create a more successful therapy. As a result the method will be more applicable to other cancers and broader populations.

Successful Gene Therapy For Melanoma

Successful Gene Therapy For Melanoma

Although adoptive cell transfer has only been used in melanoma patients so far, the researchers have shown ways to engineer cells of the immune system in a similar way to attack breast, liver cancer or lung cancers.

More information about treatment of melanoma: http://nethealthbook.com/cancer-overview/skin-cancer/melanoma/treatment-melanoma/

Reference: The Medical Post, September 19, 2006, page 1 and 61

Last edited November 1, 2014

Sep
01
2006

Prostate Cancer Recurrence Linked To Obesity

Prostate cancer affects a significant percentage of male patients in the higher age groups. Early diagnosis and treatment has shown good success rates. Early surgery in the form of a radical prostatectomy has given patients virtually a new lease on life. Radiotherapy as an alternative form of treatment has been an option for those who could not undergo surgery. Once the treatment is completed there is reason for optimism, if the tumor could be removed in total.

Dr. Sara Strom, PhD and research colleagues from the M.D. Anderson Cancer Center in Houston, Texas analyzed findings of 873 patients over the course of 14 years with localized prostate cancer who had received external beam radiotherapy as their sole treatment. The objective was to determine, whether all patients were doing well, or whether some could be more at risk. It turned out that those with normal body weight fared best. 27% of them experienced a recurrence of the disease. Those who were overweight had recurrence rates that jumped to 55%. Those who were obese were most severely affected with recurrence rates of 99%. The researchers believe that there is a difference of tumor behavior between patients with normal body weight and those who are overweight or obese.

Prostate Cancer Recurrence Linked To Obesity

Prostate Cancer Recurrence Linked To Obesity

Future studies will be needed to evaluate the relationship of obesity with dietary factors, genetic modifiers of steroid androgen metabolism, insulin and insulin like growth factors. This will clarify the underlying mechanism of action in the development of prostate cancer.

More information about prostate cancer: http://nethealthbook.com/cancer-overview/prostate-cancer/

Reference: The Medical Post, August 22, 2006, page 41

Last edited November 1, 2014

Sep
01
2006

Cartoons Help Kids Deal With Pain

Shots in early childhood are often approached with a sense of trepidation by parents. It means almost without fail, that there is crying and resistance. All the well meaning comments, that it is “only like a little mosquito bite” to get a shot at the clinic are of not much use.
Italian researchers were able to confirm that children feel significantly less pain from blood draws when their mother was at their side. But this study from Siena, Italy also suggests that there are additional ways to distract children from pain. Sixty-nine children aged 7-12 were observed, and the study suggests that TV cartoons have an even greater power to distract youngsters from pain. Researchers took note that children whose attention was focused on a cartoon reported only one-third of the pain reported by controls of those who did not watch a cartoon.
The practical application could be useful in labs or clinics, where children are receiving injections or may experience pain and discomfort. A funny cartoon may take some of the sting out of the dreaded shots!

Cartoons Help Kids Deal With Pain

Cartoons Help Kids Deal With Pain

The study originally appeared in the August 17 online edition of Archives of Diseases in Childhood.

More information about pain: http://nethealthbook.com/neurology-neurological-disease/pain/

Reference: National Review of Medicine, August 30,2006, page 11

Last edited November 1, 2014

Jun
01
2006

Screening Colonoscopy Highly Effective

The proverbial “ounce of prevention” can be very crucial when it comes to cancer screening methods. Cancer screening has been in the forefront for some time. Early disease detection is not only crucial for successful treatment; it can be a lifesaver!
Effective screening methods are available for some forms of cancer. Mammography screening for breast cancer and rectal examination and PSA tests for prostate cancer are methods that have received attention in the media.
Screening the large intestine for colon cancer by performing a colonoscopy has not made inroads, but new statistics point out the benefits. A colonoscopy will examine the colon for irregularities, namely the formation of polyps. Polyps are initially harmless and non-cancerous, however over time, some polyps have the potential to turn cancerous. In a colonoscopy examination, small polyps can be removed immediately, and this “weeding out” process is a highly effective preventative method against colon cancer. Research has shown, that one colonoscopy that is performed in a middle-aged patient (in his 50’s or 60’s) decreases the risk of developing colon cancer quite significantly. If no polyps are found in the initial screening, it is safe to assume that no colon cancer will present itself for 10 years.

Dr. Harminder Singh and associates from Cancer Care Manitoba and the University of Manitoba, in Winnipeg Manitoba/Canada, analyzed data of the Manitoba Health’s physicians’ database where 35,975 patients had undergone a colonoscopy, but were negative for colon cancer.These colonoscopies took place between April 1, 1989, and December 31, 2003 and follow-up was for 10 years. The end point was death or diagnosis of colon cancer.

One Screening Colonoscopy Guarantees Low Colon Cancer Risk for 10 Years (modified JAMA. 2006; 295: p.2366-2373)

 

 

 

 

 

 

 

 

This retrospective study showed the following results depicted in the modified graph bar. Patients who were negative in the beginning of the study had a reduction of colon cancer rates of 72% at the 10-year point when compared to those who had no colonoscopy. This is quite an astounding finding. Even at the 5-year point there was a reduction of colon cancer risk by 45% from a single colonoscopy. This would indicate that a person should have a colonoscopy at about the age of 50 to establish freedom of colon cancer. This could be repeated only every 10 years to ensure that no colon polyps and colon cancer develop in the meantime. This should be definitely done in patients who have a family history where colon cancer occurred in a first relative such as mother, father, brother or sister, where specialists say screening should be done every 3 years. In this familial form of colon cancer they should also have a colonoscopy done earlier (at age 40 or earlier). However, this data would indicate that in everybody such colonoscopy screening would be beneficial as it is one of the most common cancers in men and women and other tests are not reliable at this time.

More information about colon cancer: http://nethealthbook.com/cancer-overview/colon-cancer/

Reference: JAMA. 2006;295: page 2366-2373

Last edited Nov. 1, 2014

Jun
01
2006

Ginger Kills Ovarian Cancer

Active substances in ginger are killing cancer cells in lab experiments. This is the gist of laboratory studies led by Dr. J. Rebecca Liu at the University of Michigan Medical School. The findings on these studies were presented at the annual meeting of the American Association for Cancer Research.
In the past it has been implied that the substances (6)-gingerol and (6)-paradol interfere with carcinogenic processes. Gingerol also has been linked with antioxidant and anti-inflammatory properties.
The research group from Ann Arbor used whole ginger extract which was standardized to a contents of 5% (6)-gingerol to explore the death of ovarian cancer cells in vitro. They suggest that ginger can circumvent chemoresistance.

Due to this quality ginger substances can be effective in cancer cells that have been resistant to chemotherapy.

Ginger Kills Ovarian Cancer

Ginger Kills Ovarian Cancer

Other substances and their effect on cancer cells that are closer examined by the researchers are resveratol and curcumin.

More information about ovarian cancer: http://nethealthbook.com/cancer-overview/ovarian-cancer/

Reference: The Medical Post, May 9, 2006, page 15

Last edited Nov. 1, 2014