Feb
08
2015

Preserve Your Memory

At the 22nd Annual A4M Las Vegas Conference in mid December 2014 Pamela Smith gave a presentation entitled ”How To Preserve Your Memory At Any Age”. She gave a comprehensive overview of what you can do to prevent Alzheimer’s disease. The better we understand the causes of Alzheimer’s the more we can interfere with the biochemical processes that lead to Alzheimer’s or dementia. Various parts of the brain have different functions like pattern recognition, interpreting auditory and visual stimuli and so on. In the past researchers thought that after the brain development it would be stationary until we die. But they have now shown that instead the brain continues to develop even after the teenage years. New brain cells can develop as long as we live and new synapses, the connections between brain cells can form all the time.

A lack of sleep causes insulin levels to rise, which causes a lack of memory. Alzheimer’s disease has been termed diabetes type 3 because of this close connection of memory loss and uncontrolled blood sugar levels. In fact diabetics are three times more likely to develop Alzheimer’s disease.

Subunits of the brain and neurotransmitters

There are several subunits of the brain like the hypothalamus, thalamus, hippocampus and the amygdalae, which are important for normal brain function and memory. The hippocampus in particular is a major memory-processing unit, which indexes, constructs and rearranges memories.

Apart from the anatomy of the brain, neurotransmitters are important for the proper functioning of the various parts. Although there are more than 100 of them the most important neurotransmitters are acetylcholine, GABA, glutamate, dopamine and serotonin. Each of these neurotransmitters binds to only one specific receptor before a neuron sends a signal to the next. There is a decline in the speed of neurotransmission with age and also a memory decline. Compared to the memory in a young person a person at the age of 75 has a decline in memory function of about 40%.

Why do people experience memory decline?

Apart from genetic predisposition the majority of people who come down with Alzheimer’s disease do so because of neglecting the body and their brain. Neglecting elevated blood pressure by not treating it properly with medication will lead to vascular dementia. As already mentioned earlier hyperinsulinemia (too much insulin in the blood) from obesity, untreated type 2 diabetes and metabolic syndrome is another mechanism.

There is an association of lack of exercise with a higher risk of developing Alzheimer’s, so is insomnia and a lack of sleep (less than 7 hours per night). With aging there is often poor nutrition, lack of absorption of nutrients, inflammatory bowel conditions with poor absorption of nutrients and body inflammation. A significant portion of the population is deficient for various enzymes in the methylation pathway, which can lead to high homocysteine levels and the danger of premature heart attacks and vascular dementia. Psychological health also affects memory loss, as do depression and anxiety. Toxins like heavy metals, fuels, pesticides, solvents and fluoride can over time lead to memory loss and Alzheimer’s as well.

Lifestyle habits and Alzheimer’s

There are many lifestyles that cause memory loss: too much stress (from high cortisol levels that damage the hippocampus); smoking that damages acetylcholine receptors; chronic alcohol abuse leads to memory problems from the toxic effect of alcohol on brain cells, which in turn causes a disbalance of serotonin, endorphins and acetylcholine in the hippocampus.

Lack of exercise is an independent risk factor for the development of Alzheimer’s disease. Exercise increases the blood supply of the brain, strengthens neural connections and leads to growth of neurons, the basic building blocks of the brain. Mood-regulating neurotransmitters are increased (serotonin, endorphins).

Sleep deprivation leads to memory loss, but so does the use of aspartame, the artificial sweetener of diet sodas.

Sugar consumption and too much pasta (which gets metabolized within 30 minutes into sugar) causes oxidization of LDL cholesterol and plaque formation of all the blood vessels including the ones going to the brain. On the long-term this causes memory loss due to a lack of nutrients and oxygen flowing into the brain.

Hormone changes

A lack of testosterone in men and estrogen in women interferes with cognition and memory. For this reason it is important after menopause and andropause (=the male menopause) to replace what is missing with the help of a knowledgeable health professional.

Too much DHEA from stress can decrease memory, but too little DHEA from aging can also do this. Alzheimer’s patients have DHEA levels that are 48% lower than men and women of the same age who have normal memories. Pregnenolone is a precursor of DHEA, estrogen, progesterone and testosterone. Dr. Smith called pregnenolone the “hormone of memory in the body”. At an age of 75 most people have a 65% lower level of pregnenolone than a persons in the mid 30’s. Pregnenolone keeps your brain balanced between excitation and inhibition, helps you to cope with stress and gives you energy.

Ask for input by hormone specialist

But before you consider supplementing with a pregnenolone hormone level, this should be ordered by a knowledgeable health professional. Dosing can be tricky as too much pregnenolone can result in too much DHEA, estrogen, progesterone or testosterone.

Progesterone is manufactured inside the brain, spinal cord and nerves from its precursor, pregnenolone, but in women it also comes from the ovaries until the point of menopause. Progesterone is needed in the production of the myelin sheaths of nerves and it has a neuroprotective function. In menopausal women bioidentical progesterone is a part of Alzheimer’s prevention.

Melatonin is a hormone, a powerful antioxidant and a neurotransmitter at the same time. It helps in the initiation of sleep, stimulates the immune system and protects from the toxic effects of cobalt, which has been found to be high in Alzheimer’s patients.

Other factors contributing to Alzheimer’s

Any inflammatory condition can trigger destruction of neurons, so do the beta-amyloid proteins associated with Alzheimer’s. Contributory factors can be food allergies, disbalance of gut bacteria, recreational drugs (particularly ecstasy) and certain medications. Dr. Smith stated that the most common foods causing allergies that affect the brain are: sugar, wheat, dairy, eggs, shellfish, potatoes, beef, tomatoes, corn, coffee, peanuts, roasted soy beans and yeast.

Dr. Smith mentioned that these medications can affect memory: statins, sedatives, steroids, levodopa, muscle relaxants; antihypertensive drugs, antidepressants, antibiotics, anticonvulsants, anti-arrhythmic drugs, pain relieving drugs (analgesics) and antihistamines. If you are on any of these, you may want to discuss alternatives with your doctor. Dr. Perlmutter mentioned in Ref. 1 that statins interfere with brain function and can lead to Alzheimer’s.

Promoting brain health

Medication helps only to stall further memory loss for up to 6 months, so Dr. Smith said about medications only: “much research is still needed in this area”.

On the other hand she stated that many foods, vitamins and supplements in combination could improve memory and prevent the development of Alzheimer’s disease. She spent considerable time in the remainder of her talk on details regarding foods, vitamins and supplements.

Dr. Smith said that we need to eat foods that are rich in antioxidants like blueberries, apples, raspberries, blackberries and strawberries; cherries, cranberries, cooked kale, garlic, grapes, prunes, raisins and raw spinach. But at the same time she stressed that we cannot trust the food industry anymore, and we need to buy organic foods. She gave an example of the “dirty dozen” as defined by the environmental working group (contaminated fruits and vegetables).

Food intake also applies to portions:eat 5 to 6 smaller meals per day. Consume red meat only three times per week.

The brain needs fats like nuts and seeds: walnuts, almonds, pine nuts etc.

Fish also contains healthy omega-3 fatty acids and DHA. The problem with predator fish like tuna or swordfish is that they are contaminated with mercury. But wild salmon and mackerel are still OK. A good alternative is to supplement with pharmaceutical grade EPA/DHA omega-3 capsules. They are molecularly distilled, which means they are not contaminated with mercury or PBC’s and they are more concentrated; they typically contain 1000 to 1400 mg of EPA/DHA per capsule. One to two capsules twice per day (a total of 2 to 4 per day) would be a good anti-inflammatory dose.

Specific food recommendations

Use olive oil and coconut oil for cooking; avoid the omega-6 oils (safflower oil, grape seed oil, sunflower oil, corn oil to just mention a few). These latter oils, which are heavily advertised by the food industry, create too much arachidonic acid leading to body inflammation. Your brain is very sensitive to inflammation, which causes Alzheimer’s. For the same reason avoid deep fried foods and processed foods.

There is more you need to watch for: no food additives, no artificial food colorings, no preservatives, flavors and MSG. Be alert about the food industry’s alternative “language” or terminology for MSG: “natural flavor”, “yeast extract” etc.

Preserve Your Memory

Preserve Your Memory

Brain nutrients

Dr. Smith reviewed a long list of brain nutrients that support the brain in its metabolism and prevent the development of dementia and Alzheimer’s disease.

I will only highlight the most effective and established nutrients here.

DHA: It has been known since 1999 that Alzheimer’s patients are missing DHA in their system. Molecularly distilled fish oil with high omega-3 fatty acids (both EPA and DHA) is one of the mainstays of prevention of inflammation in the body and the brain. 2 capsules twice per day of the concentrated 1000mg to 1400 mg capsules is desirable to prevent Alzheimer’s disease.

Phosphatylserine (PS): This phospholipid is part of the membrane of brain cells and controls what nutrients enter into them. It also increases the neurotransmitters acetylcholine, serotonin, norepinephrine, epinephrine and dopamine. Dr. Smith mentioned that PS is naturally present in foods like brown rice, fish, soy and green vegetables (particularly the leafy ones). The daily dosage recommended by Dr. Smith is 300 mg (note: some people develop a bothersome, but harmless bitter taste in the mouth at this dose; in this case take a lower dose like 100 or 200 mg per day).

Other supplements like Ginkgo biloba, alpha lipoic acid and others

Ginkgo Biloba: It improves blood flow to the brain and counteracts shrinkage of the hippocampus with age. Dr. Smith recommends 60 mg to 240 mg daily.

Alpha Lipoic Acid: Alpha lipoic acid is an antioxidant, helps stimulating the sprouting of new nerve cells and nerve fibers. Take 100 mg of alpha lipoic acid daily for memory.

Dr. Smith recommended many other supplements, which I will not explain in detail here: B vitamins, vitamin E and C, carnosine, acetyl-L-carnitine, boron, ginger, coenzyme Q-10 (or CoQ-10), curcumin, vinpocetine, zinc, grape seed extract, blueberry extract, Ashwaganda, glyceryl-phosphoryl-choline, SAMe, huperzine A and DMAE.

Dr. Smith discussed the benefits of CoQ-10 supplementation and reminded the audience that “whatever is good for the heart, is good for the brain”. She recommended to read Dr. Perlmutter’s book from which this phrase was borrowed (Ref. 1).

Genetic factors

Dr. Smith pointed out that there are about 5 genes that have been detected that are associated with Alzheimer’s disease and in addition the apolipoprotein E4 (APOE4). About 30% of people carry this gene, yet only about 10% get Alzheimer’s disease. This shows you how important lifestyle factors are. Physicians call this epigenetic factors. The can suppress the effect of the APOE4 gene. She also stated that our genes contribute only about 20% to the overall risk of developing Alzheimer’s disease. This leaves us with 80% of Alzheimer’s cases where we can use the brain nutrients discussed above and exercise to improve brain function.

Conclusion

Don’t wait for Big Pharma to develop a magic pill. Follow the simple steps in combination that Dr. Pamela Smith talked about in her presentation: Exercise, have organic food to keep toxins out of your body and brain, replace missing hormones with bioidentical ones and take supplements that are known to be effective (link for male menopause). In other words provide the right environment for your genes to work properly without getting Alzheimer’s disease.

Reference

1. David Perlmutter, MD: “Grain Brain. The Surprising Truth About Wheat, Carbs, And Sugar-Your Brain’s Silent Killers.” Little, Brown and Company, New York, 2013.

Jan
16
2015

Telomere Length A Telltale Sign Of Aging

Dr. Sandy Chang gave a talk at the 22nd Annual World Congress on Anti-Aging Medicine in Las Vegas Dec. 10-14, 2014 entitled “Telomere measurement as a diagnostic Test in cardiovascular and Age-related disease”, but a shorter title would be “telomere length a telltale sign of aging” (my choosing).

Dr. Chang pointed out that it is now well established that telomere length is directly related to health. The shorter the telomeres are the higher the probability to get the following: early menopause, infertility, diabetes, wrinkles, arthritis, osteoporosis, cardiovascular disease, Alzheimer’s, Parkinson’s, dementia, cancer, stress and a lack of stem cells. In this BMJ study from 2014 it was shown on a large population basis that shorter white blood cell telomeres lead to a higher risk of coronary heart disease causing heart attacks. Decreased telomere length is also associated with the development of breast cancer, cancer of the ovary and uterus, cancer of the prostate and skin cancer.

Because of these connections it makes sense to determine a person’s telomere length. If it is short, do check-ups more often to detect any cancer early when it can still be treated.

Telomere length measurements are now done in many infertility clinics as short telomeres both in the male and female is associated with infertility.

The newest finding and perhaps the most important is that a healthy lifestyle, vitamins and supplements can elongate telomeres while a poor lifestyle leads to shortening of telomeres.

Here are the factors that lead to shortening of telomeres:

– Chronic stress

– Poor diet and nutritional habits

– Chronic inflammatory diseases

– Metabolic disorders

– Lack of consistent exercise/sedentary lifestyle

– Obesity, high BMI and body fat

– Smoking

– Over consumption of alcohol

– Lack of sleep / insomnia

When short telomeres are detected, it is important for the physician to look at lifestyle changes to protect telomeres from decreasing their length even further. This has the potential of preventing dementia and Alzheimer’s when it comes to brain health. It can prevent osteoporosis and metabolic diseases (diabetes, metabolic syndrome). Telomerase is the buzzword today, which is an enzyme that all of our cells have. The purpose why we have telomerase in our cells seems to be helping us build up and repair telomeres. Any substance that preserves telomerase or prevents the breakdown of telomerase will prevent shortening of telomeres and will also prevent the above-mentioned diseases.

These supplements lead to lengthening of telomeres:

-Vitamin C and E

-Omega-3 and polyphenols

-Vitamin A and D3

-All of these help controlling oxidative stress, reduce DNA damage, reduce inflammation and build up telomere length.

-A good diet and nutrition (Mediterranean type diet) will prevent telomere shortening as well and also lead to telomere lengthening.

-T-65, an extract from astragalus has been shown in vitro to lengthen telomeres, but there is no publication yet about in vivo effects in humans.

-Resveratrol is useful to prevent shortening of telomeres as well.

-Exercise also is a simple means to prevent telomere shortening.

Telomere Length A Telltale Sign Of Aging

Telomere Length A Telltale Sign Of Aging

Another talk on telomeres was given by Dr. Harvey Bartnof with the title “Telomere Shortening and Modulation: Case Studies From The Clinic”.

This talk was a comprehensive review of what is known about telomeres, about the fact that many diseases are due to telomere shortening, about animal experiments, ways of how to lengthen telomeres and finally some data on human studies with regard to telomere lengthening.

In the following I will briefly review all of these areas that were discussed. Some of this material overlaps with Dr. Chang’s lecture.

What produces telomere shortening? Dr. Bartnof showed 4 slides that listed all of the conditions and diseases that are associated with telomere shortening. Telomere shortening is associated with twice the risk to die from a heart attack when compared to people with normal telomeres.

a) Known genetic conditions in humans associated with telomere shortening

There are three known genetic conditions due to telomere shortening: A premature aging syndrome, called dyskeratosis congenitalis; patients with this condition die prematurely from cancer, or from bone marrow failure.

People with Werner syndrome who have a genetic telomere loss have a mean life expectancy of only 54 years.

Idiopathic pulmonary fibrosis is another genetic condition with shortened telomeres due to mutations.

b) Telomere shortening associated with these health conditions

Professor Elizabeth Blackburn, PhD who is one of the three researchers who won the Nobel Prize in Physiology and Medicine for their work on telomeres in 2009 stated the following: “Telomere shortness is associated with just about all the major diseases of aging… from cardiovascular disease, death from cardiovascular disease, risks of cardiovascular disease, diabetes, diabetes risks such as insulin resistance, vascular dementia, to osteoarthritis.”

An enormous amount of clinical investigations have been done since in cohort groups like people with diabetes, high blood pressure, obesity and cancer.

There is natural shortening of telomeres due to the aging process. When we compare telomere length of body cells of a 20-year old and call this 100%, the telomeres of a 100-year old person are on average only 40%. A study from the Karolinska Institute found in a group of matching twins where one twin had shortened telomeres, this twin had a 2.8 times greater risk of death than the twin with normal telomere length.

However, as already mentioned a number of other factors can lead to shorter telomeres like chronic stress in workers who look after Alzheimer patients, being of the Caucasian race (compared to African-American), having had less education, chronic unemployment, depression, pessimism, single people versus married people, phobic anxiety in women and hostility in men, poor sleep and too little sleep, migraine headaches in women, low physical activity, smoking cigarettes and alcohol consumption. The list does not stop here. Other conditions are associated with telomere shortening like heroin abuse, exposure to smog, polycyclic aromatic hydrocarbons and lead, cardiovascular disease, diabetes, cancers, osteoporosis, osteoarthritis, rheumatoid arthritis, cirrhosis of the liver, inflammatory bowel disease, chronic obstructive lung disease, Alzheimer’s disease, Parkinson’s disease, chronic kidney disease and disability in the elderly.

c) Effects of medications on telomere length

Antidepressants used against depression have a telomere lengthening effect, but NSAID’s, aspirin and interferon-alpha shorten telomeres. Other telomere shortening effects come from cancer chemotherapy.

d) Telomerase activation elongates telomeres

Successful experiments in various mouse strains showed that special strains that were telomerase deficient, could be reconstituted to normal by reinserting telomerase: atrophied organs regrew back to normal size and function. In humans it was shown that increased physical activity elongated telomeres, so did vitamin C, E and vitamin D3 supplementation, resveratrol, a Mediterranean diet, marine omega-3 fatty acid supplementation, higher fiber intake, bioidentical estrogen in women and testosterone in men, relaxation techniques like yoga and meditation. The Astragalus-derived telomerase activator TA-65 has been shown in animal experiments to elongate telomeres. The human data about TA-65 is still spotty or not available (it is also very expensive and may be unnecessary given the fact that so many other agents are known to lengthen telomeres).

e) Human data on telomere lengthening

Much can be achieved by changing one’s lifestyle: cut out toxins like cigarette smoking and alcohol abuse. Get involved in a regular exercise program, which has been shown to increase HDL cholesterol and to elongate telomeres. Adopt a Mediterranean type diet including olive oil; take vitamin E, D, C and supplements with resveratrol and murine omega-3 fatty acids, all of which elongate telomeres. Get enough sleep (7 to 8 hours per night) and do yoga and meditation. Avoid distress and tone down your stress level to eustress (normal stress level associated with every day living). An older person should use bioidentical hormones to replace missing hormones. All of this taken together will create a milieu in your body where telomeres get elongated and you live longer without disease. Several clinical conditions were mentioned where baseline telomere length was assessed initially and was found to be too short; simple lifestyle changes were then initiated, which were able to improve telomere length and treat these diseases successfully. In addition TA-65 (also termed T-65) was given in some of these cases, but in a subsequent discussion Dr. Bartnof admitted that he could not comment on how effective TA-65 by itself was as it was only one component of many other effective telomerase stimulators given. Till further research is out on this substance, it may be just very costly without spectacular benefits on its own.

Conclusion

I gave a summary of the talks by Dr. Chang and Dr. Bartnof regarding telomeres, but these were not the only talks about telomeres, although quite representative for the others. Both speakers pointed out how powerful lifestyle is for our body functions as this is what lengthens our telomeres and allows us to live longer, disease-free lives. Stem cells also have telomeres, but they are on average longer than the rest of the body cells (called somatic dells). An improved lifestyle will keep our stem cells in good shape, so they are there when needed to replace aging somatic cells.

The new logic of a healthy lifestyle is:

A healthy lifestyle causes healthy telomeres of somatic cells and of stem cells; this causes health until a ripe old age. In the next few weeks I will blog about more topics from the 22nd Anti-Aging Conference in Las Vegas. Stay tuned.

Jan
04
2015

Lifestyle Has Profound Changes On Our System

Dr. David Katz delivered a keynote address where he said that lifestyle has profound changes on our system. This took place at the 22nd Annual World Congress on Anti-Aging Medicine in Las Vegas Dec. 10-14, 2014. His talk was entitled “Integrative Medicine: A Bridge Over Healthcare’s Troubled Waters”.

He started the 1 hour talk with showing a slide of six blind men and the elephant. The conclusion was that each of the blind men saw only one aspect of the elephant, but no one saw the true elephant. With healthcare it is a bit like that.

Causes of death

Dr. McGinnis et al. in 1993 published the “Actual causes of death in the United States”.

Ten factors were responsible for chronic disease, but the first three things on McGinnis list were the most important ones: tobacco use, diet and lack of exercise.

Mokdad in 2004 noted that the revised list of “Actual causes of death in the United States”: tobacco was no longer number one.

Effect of healthy lifestyle

Ford et al. in 2009 stated: “Healthy living is the best revenge…Nutrition-Potsdam study

Although there is no magic pill for reducing disease, lifestyle is exactly “the magic pill” that reduces mortality by almost 80%.

Fastforward to 2014: Akkeson et al. came to the same conclusion when examining what would be able to prevent heart attacks. They stated that LIFESTYLE is what matters.

We live in the “epigenetic age: dinner is destiny!” With this Dr. Katz meant to say that our genes get switched on and off depending on what we put into our mouths. This determines whether we live shorter or longer lives.

He went on to say: “Feet (exercise), forks (diet), fingers (cigarettes) are what matters.” Oncogenes can get turned off in prostate cancer with the help of exercise, the right food intake and quitting to smoke.

Food addiction and obesity

Dr. Katz mentioned the book by Michael Moss “Salt, sugar, fat”, which made it to the cover story of Time Magazine in 2013. In it is described how the food industry employs PhD’s to include agents in processed foods to ensure that consumers get addicted to the food products. Food addiction leads to obesity; the CDC statistics show that it is effective! We have put up with this for far too long. There are differences of obesity rates between countries, here Canadian and US statistics shown.

Dr. Katz asked the audience to raise up their hands, if they had a person close to them die of cancer, a heart attack or a stroke. Almost all of the more than 500 participants in the Hall raised their hands.

Lifestyle Has Profound Changes On Our System

Lifestyle Has Profound Changes On Our System

Children education programs

So what is the ONE thing that can fix everything? He answered this rhetoric question by saying that there is no one thing that fixes everything. But we can start at a young age by educating our children. Dr. Katz has started a program for school kids called “ABC for fitness for kids” to prevent obesity. The program teaches children healthful food choices. Dr. Katz commented that a website, NuVal uses a nutritional value rating system to monitor food quality and manufacturers have improved the content of their products because the composition of their products were displayed on that website. We need to be vigilant and read labels.

Change one thing at a time

But we can only change one thing at a time, like we walk one step at a time on a spiral staircase to get to the next floor. We ask ourselves about our lifestyle: what is the first thing to fix? We fix this point (like exercise more), then we fix the second (adopt a Mediterranean diet), the third (take specific vitamins and supplements) and so on; in other words we approach one thing at a time. Integrative medicine, the fusion of conventional and non-conventional medicine, can help to solve problems one step at a time.

Effect of CoQ10

Despite a bias in the North American medical literature saying that CoQ10 was “useless”, the European Heart Journal reported in 2013 that CoQ10 decreases all-cause-mortality in patients with heart disease. Here is a link to a more recent article (Dec. 2014) regarding a two year trial with congestive heart failure patients taking only 100 mg of CoQ-10 three times daily that found that all-cause-mortality was reduced significantly.

Blue zones

There is a new wave going around the United States: It is the idea to copy the lifestyle of the blue zones around the world. Blue zones are areas in the world where the life expectancy is 100 years or more. This link leads you to a information about blue zones that is worth watching.

It explains how Blue Zones are being established all around America. Dr. Katz explained that lifestyle is the medicine and the environment is the spoon. In Blue Zones the environment is such that people who live long, healthy lives influence you positively. They spoon it to you non-verbally by their example. Organic vegetables in stores are cheaper in Blue Zones, so it is easier to eat more of them; people socialize more with each other, they exercise more and dance. This is what people do who live longer than 100 years. In other words, you change the culture, you change your lifestyle, you exercise more, you stop smoking, you eat healthy and you live longer.

You must decide on which pathway to go

Dr. Katz ended his lecture with the image of you walking along and coming to a fork. To go further you must decide to go on the pathway to your right or on the pathway to the left. You turn on the right pathway by deciding to adopt the principles of the Blue Zones; you make the decision to want to turn older than 100 years and keep your vitality until it is time for you to pass on. In the meantime you enjoy every day, you are not disabled and your mind and body stay healthy. The other pathway was the one that the majority of the industrialized Western nations has taken in the last few decades. Which path will it be that you decide to take?

Conclusion

At the conference Dr Katz and a number of other speakers pointed out how powerful lifestyle is for our body functions. Other speakers stressed the importance of telomeres, the caps of the chromosomes, which comprise the end of the double stranded DNA. With every cell division our telomeres shorten. Stem cells also have telomeres, but they are on average longer than the somatic dells. It probably is like this to be able for stem cells to replace the aging somatic cells.

There is a new logic of a healthy lifestyle is. It says that a healthy lifestyle causes healthy telomeres of somatic cells and of stem cells. This causes health until a ripe old age. I will be blogging about some of the other key talks of the conference in the near future to clarify this point further.

Sep
03
2014

Probiotics Are Important For Your Health

We need to be aware that probiotics are important for your health. Growing up in Germany after World War II I remember that occasionally there were interesting newspaper headings. It  showed an older person in the nineties when the average life expectancy was in the late 60’s. The reporter asked, “What did you do to turn that old?” The answer was that the person always ate a lot of yogurt.

This did not sink into mainstream medicine at that time and people did not really believe this statement. How could eating yogurt make a person live longer?

Fast forward to 2014. You read about probiotics in magazines, on the Internet, and even TV commercials expose you to it.

In the Wikipedia it is accepted that yogurt can help seniors who have a lower bifidus bacteria population in their colon to rebalance their gut flora, which will prevent colon cancer. It also describes that yogurt can help yeast infections in women.

In the meantime probiotics have been developed and concentrations like 20 to 80 billion bacteria per capsule with a mix of Lactobacillus and Bifidobacterium species are available in the health food store for prevention.

The medical profession has studied the effects of higher potency probiotics and came to the conclusion that probiotics have indeed effects on the body far beyond the gut.

Here are a few highlights.

Bowel disease improves

In cases of bacterial or viral diarrhea the frequency of bowel movements and the intensity of bowel cramps gets helped within a few days, and recovery from the diarrhea is much faster with probiotic than without. Patient with irritable bowel syndrome and ulcerative colitis are helped with probiotics. Probiotics help both constipation and diarrhea in otherwise healthy people as well.

Immune system booster

The small bowel contains clusters of immune cells within the bowel wall. Together they are a formidable immune organ in the gut, which connects to the blood and the rest of the immune system throughout the body (lymph glands, spleen, bone marrow). Specifically it has been proven in humans that macrophages, natural killer (NK) cells and cytotoxic T-lymphocytes, which are the working horses of the immune system, are all stimulated by probiotics.

Less respiratory infections

School children who were given 1 capsule of probiotics twice per day for 3 months and flu symptoms and absenteeism were observed due to colds and flus. When they did get a viral infection, the illness had a shorter course, resulting in much less school absenteeism over the course of the trial when compared to a placebo group. It seems that a healthy gut flora stimulates the immune system to work at its best.

Cancer prevention

To a certain degree cancer can be prevented by probiotics and other nutritional factors. Breast cancer is one of the cancers where probiotics have been shown to be effective in reducing disease.

Apparently the probiotic bacteria bind to the cancer causing factors (carcinogens) that some of the bad gut bacteria produce. Probiotics also suppress other bacteria that convert pro-carcinogens into carcinogens. This is not all: the probiotics also interfere with enzymes involved in the production of carcinogens in the gut. This stimulates the gut immune cells to produce cytokines that are needed in the battle against early cancer. Probiotics play a role in multiple processes that help the body to fight cancer, not only in the gut, but also in the rest of the body!

Helps diabetes get better

How can gut bacteria help diabetes, which is an endocrinological disease? Both human and animal studies have shown that insulin resistance is improved by probiotics. In a 6-week study both blood sugar levels and hemoglobin A1C values (that measure long-term control of diabetes) dropped significantly by eating 300 grams of yoghurt per day when compared to a control group who did not.

Obesity

Probiotics given to mothers at least one month prior to birth and at least up to 6 months after birth prevented excessive weight gain in both the mothers and their children. In addition, probiotics can suppress a lot of the inflammatory substances in obesity.

Probiotics reduce cardiovascular risk

Several studies have shown that probiotics lower LDL cholesterol, total cholesterol and inflammatory markers in the blood stream resulting in lower risk for hardening of the arteries.

One should not look at probiotics as a single factor for prevention of heart attacks and strokes. Combine probiotics with exercise and a low refined carbohydrate diet. High sugar and starch diets lead to absorption of sugar in the stomach and small intestine. This results in a lack of nutrients to support the gut flora. Combine probiotics with vegetables and lettuce. Then you have the proper mix of fiber, minerals and other nutrients to sustain balanced bacteria in the bowels. This prevents heart attacks and strokes and keeps inflammatory markers down. I have blogged about this before and stated that the combination of organic food (to avoid antibiotic residues in our diet), fruit and vegetables combined with probiotics will protect you from heart attacks and strokes.

Probiotics Important For Your Health

Probiotics Are Important For Your Health

Conclusion

Maybe the newspaper articles in Germany after the Second World War were right. There is something in yogurt (Lactobacillus and Bifidobacterium species) that can make you live longer. The explanation seems simple: add probiotics to your diet.  You will have a better immune system and get less respiratory infections. But you also prevent heart attacks, strokes and prevent obesity and cancer. All of this in combination will lead to healthier lives, and more people will live to tell about it.

Last edited Sept. 3, 2014

May
21
2014

Forty Percent Of Premature Deaths Can Be Prevented

A new report from the CDC (Center of Disease Control) in the US has revealed that up to 40% of premature deaths could be prevented by simple lifestyle changes. As this link shows every year about 900,000 premature deaths occur in the US, which are due to 5 major diseases that in the opinion of the CDC can be prevented by 20 to 40%. Here are the diseases that kill: cancer, heart disease, COPD/emphysema, stroke and accidents/injuries. These conditions were responsible for 63% of all deaths in the US in 2010.

Let’s discuss each of these conditions and how one could lower the risk of dying from them.

1. Cancer:

The Framingham Heart Study has shown that smoking and cancer are closely related. Smokers who quit can significantly reduce their risk of getting cancer. We also know that exercise and prophylactic supplements like fish oil and vitamin D3 have cancer preventative effects.

Antioxidant supplementation that included beta-carotene, vitamin A, vitamin C, and vitamin E daily or on alternate days for 1 to 12 years, along with selenium supplementation reduced the incidence of cancer of the esophagus, colon, pancreas, stomach or the liver. Insulin resistance due to sugar and starch overconsumption is causing cancer, particularly breast cancer, colorectal cancer and endometrial cancer. I have discussed this in a recent blog.

Pollution has been linked to increased lung cancer risks as discussed here.

2. Heart disease:

Heart disease can be caused by several factors in combination. Lifestyle issues are important: Smokers need to quit smoking as the Framingham Heart Study has shown more than fifty years ago that smoking causes heart attacks. Obesity and diabetes also contribute significantly to the risk of heart disease. Often these are connected to faulty nutrition, which is another lifestyle issue that comes to mind when too much sugar and starchy foods are taken in; your liver will convert these into fatty acids, triglycerides and elevated, oxidized LDL cholesterol, which gets deposited under the lining of the arteries. A lack of exercise adds to this problem as a lack of exercise lowers the protective HDL cholesterol and fat is deposited under the lining of the arteries. Start exercising and your protective HDL cholesterol will rise, your total cholesterol to HDL ratio will lower to healthier levels and your risk for hardening of the arteries and for getting a heart attack will fall. If you have diabetes, it is important that you manage your blood sugars well; this means that if you inject insulin, you want the blood sugar tests to be within the normal range and the hemoglobin A1C values to be below 5.5%. Poorly controlled diabetes is an important cause of heart attacks and strokes. High blood pressure is also an important cause of developing heart attacks and strokes. It is important to control your blood pressure by taking blood pressure lowering pills and also by exercising regularly. Exercise seems to send a signal to relax the blood vessels thus lowering the blood pressure, which in turn prevents heart attacks.

Forty Percent Of Premature Deaths Can Be Prevented

Forty Percent Of Premature Deaths Can Be Prevented

 

3. COPD/emphysema:

Chronic obstructive pulmonary disease (COPD) or emphysema is mostly caused by chronic exposure to cigarette smoke from smoking. The earlier you can quit, the better your chances that your breathing will not be the limiting factor when you age. But it is also important to avoid exposure to other noxious gases, such as from welding and from exposure to pollution. This may involve a decision to move to a less polluted area. Or it might involve a job retraining. Those who are suffering from COPD can be helped to a certain extent by a portable oxygen tank with nasal prongs.

4. Stroke:

As mentioned before, quitting smoking, controlling high blood pressure and controlling blood sugar, if you suffer from diabetes have been shown to stabilize your blood vessels including the ones that supply your brain. The key is to prevent hardening of the arteries by a healthy lifestyle. Exercising and keeping your weight under a body mass index of 25.0 have been shown to be effective stroke prevention. Healthy nutrition as indicated above under “heart disease” is equally important for stroke prevention. Go green (eat more vegetables, consume more green smoothies), cut down grains, sugar and starchy foods and you will live longer without strokes and heart attacks. Remember, what’s good for your heart is good for your brain!

5. Unintentional accidents/injuries:

Wearing helmets when bicycling, wearing seat belts when driving in a car, avoiding risky behaviors are all measures that save lives. One factor stands out in all of this: if you drink too much, you run the risk of being involved in unintentional accidents or injuries. People may not like to hear this, but your brain lacks the natural inhibitory impulses when you are under the influence of alcohol, so you become more daring and you may not pay attention for the split second that could have prevented an injury or accident. People react very differently to alcohol. Some people feel inebriated after only ½ a glass of wine or beer whereas others can drink more before they make mistakes. The best is to be sober when you drive, ski, use power tools or walk in traffic. Even climbing ladders requires a clear mind!

Conclusion:

As the CDC said 20 to 40% of premature deaths (deaths that occurred before the age of 80) could have been prevented, if the above-mentioned recommendations were followed. Let me rephrase this: 180,000 to 360,000 premature deaths every year in the US before the age of 80 could have been prevented! Curative medicine cannot help with these statistics as a heart attack or stroke has happened when it has struck you. Cancer and end stage lung disease are similar conditions that you are suddenly faced with when they occur and unintentional accidents just seem to happen. This is where the importance of prevention can be seen, because these little baby steps every day are adding up to something formidable, a force to be reckoned with. Be part of the solution, think prevention!

More information on:

1. Cancer mortality: http://nethealthbook.com/cancer-overview/overview/cancer-mortality-rate/

2. Higher vitamin D3 intake lowers mortality from heart attacks, strokes, cancer, fractures due to osteoporosis: http://nethealthbook.com/news/higher-vitamin-d-levels-associated-lower-risk-mortality/

Last edited Nov. 8, 2014

Apr
05
2014

Yes, There Are Healthy Sugar Substitutes

It is true that sweets are not good for you because they lead to fat accumulation and to diabetes. I explain how this works later in this blog. But who says you cannot sweeten your life with healthy ingredients? Not all sugar substitutes are the same; some are awful, some are in between and one is good (see below).

General information why sweets and starches are bad for you:

There is a triple whammy from sweets that you don’t really want:

a) First, sugar gets absorbed really fast through the gut wall and arrives in your blood stream within 15 to 20 minutes. Starches can be just as powerful in terms of blood sugar surges, but it takes perhaps 30 to 40 minutes for the peak of blood sugar to occur. The end result is the same: whether you load up with a pizza, a doughnut or drink a large, sugar-loaded soda drink, your pancreas reacts the same way. It produces a lot of extra insulin to bring the blood sugar level down. When you do this day after day your pancreas gets used to overproducing insulin and you develop insulin resistance meaning that your insulin receptors that are on every cell surface get tired and become less sensitive to insulin. Due to insulin resistance the muscle cells and the liver cells do not take up sugar (in the form of glucose) as easily as before.

b) Second, because excess sugar cannot be stored as glycogen (the storage form of glucose in the liver and the muscles), the liver converts excess glucose into triglycerides and oxidized fatty acids get taken up by white blood cells called macrophages. These attach to the inner lining of the arteries and lead to atheromatous plaques, the first stage of hardening of the arteries.

c) Third, glucose is an oxidizing agent that will oxidize LDL cholesterol. This makes the LDL particles much denser and forms the so-called very dense LDL lipoprotein fraction (VDLDL) that can be detected in special blood tests (Ref.1).

Not surprisingly people who consume sugar, sweets, soft drinks and starches on a regular basis will have very dense LDL particles (=VDLDL, also called “pattern B-LDL”). The treatment for this is to quit sugar and starchy foods.

I have explained in more detail what sugar does in this blog.

Yes, There Are Healthy Sugar Substitutes

Yes, There Are Healthy Sugar Substitutes

The food industry’s answer to low carb diet drinks and low sugar foods:

Many years back the food industry decided to offer alternative diet drinks that would not contain sugar, but instead have aspartame in it.

Dr. Blaylock has researched excitotoxins like MSG and aspartame (NutraSweet) and urges you in this link to abandon both. I agree with him. But while we are at it, don’t take other artificial sweeteners like sodium cyclamate in Canada (Sweet’N Low). Are you thinking of taking sucralose (Splenda) instead? Think again. What the industry seems to have forgotten is that it was originally developed as an insecticide. This website states that sucralose was actually discovered while trying to create a new insecticide. A researcher tasted it and found it exceedingly sweet. I have done the experiment myself in Hawaii where small ants are ubiquitous. I thought I take a package of Splenda from a coffee shop and do the experiment: In the beginning the ants were reluctant to eat it, but after a few hours they came and took it in. One day later there were only shrivelled up dead ants left in the area where Splenda had been sprinkled. Proof enough for me that Splenda was developed as an insecticide!

In the Splenda marketing scheme they decided to first introduce Splenda gradually into diabetic foods as a sweetener, then later sell it to the public at large. Don’t fall for it. It was a side product of insecticide research, and insecticides have the undesirable quality of being xenoestrogens, which block estrogen receptors in women. As a result of that estrogen can no longer access the body cells, including the heart. The final consequence for a woman is a higher risk for cardio-vascular disease. This can cause heart attacks, strokes and cancer. In men estrogen-blocking xenoestrogens can cause breast growth and cause erectile dysfunction.

The natural sweeteners:

One wonders why the food industry did not choose healthy sweeteners like stevia that has been used for decades in Japan and South America.

Other sweeteners like xylitol, sorbitol, maltitol, mannitol, glycerol, and lactitol are sugar alcohols. Contrary to what many believe they have calories, but much less than sugar, so they are perceived as “safe” as a dietary supplement for weight loss. These alcoholic sugar compounds still produce partial LDL oxidization; interfere with weight loss and still lead to a certain insulin response.  Stevia, a natural sweetener from a leaf of South America is safer and without any calories.

The key is that stevia will not oxidize your LDL cholesterol and will not cause a hyperinsulinism response following a meal. It is metabolically neutral. It is the ideal sweetener for people who desire to lose some weight. It is also safe as it is no excitotoxin. The FDA has recognized stevia as “generally recognized as safe” (GRAS).

What about fructose, agave syrup, honey, brown rice malt syrup, fruit juice concentrates, refined fructose, maple syrup?

The problem is that they are all sugars, which cause a full insulin response leading to obesity, diabetes and hardening of the arteries. This causes heart attacks and strokes. These natural sugar products also oxidize LDL cholesterol, which initiates plaque formation as discussed above; this is the first step leading to hardening of the arteries. It took the medical profession 30 years of observing that a low fat/high carb diet makes us fat and causes heart attacks, leads to strokes and causes diabetes. Let’s not make the mistake of trusting the food industry and mindlessly swallow so-called natural other sugars and sugar substitutes like xylitol, sorbitol, maltitol, mannitol, glycerol, and lactitol. You may want to chew the odd gum with xylitol, as this will prevent cavities in your teeth. But otherwise it is much safer to just stick to Stevia to sweeten your tea, coffee or food. There are brands that are less bitter than regular stevia products, like stevia from New Roots in Canada and stevia from KAL in the US (no, this is not a commercial, it is based on my own observations).

Conclusion:

Sugar is an emotional topic that can get people caught up in heated discussions. The sugar industry and the sugar substitute industry have also powerful lobby groups that provide the Internet and the popular press with conflicting stories to convince you to buy their product. This blog was meant as a no-nonsense guide to get you removed from the high-risk group of candidates for heart attacks, strokes or diabetes. Let’s not forget the metabolism behind the various sugars and starchy foods described above, which I have explained in more detail in my recently published book (Ref.2). Forget the emotions of severing yourself from your favorite fix and stick to a tiny amount of stevia that can replace the familiar sweet taste that you have become accustomed to from childhood onward. At least this is what I do. The only alternative would be to take the plunge and cut out any sweet substance altogether, which I am not prepared to do. If you can do it, by all means go ahead.

More information on carbohydrates: http://nethealthbook.com/health-nutrition-and-fitness/nutrition/carbohydrates/

 

Reference:

1. Life Extension: Disease Prevention and Treatment, Fifth edition. 130 Evidence-Based Protocols to Combat the Diseases of Aging. © 2013

2. Dr. Ray Schilling: “A Survivor’s Guide to Successful Aging“, Amazon.com, 2014

Last edited Nov. 7, 2014

Mar
08
2014

Protecting Yourself From Environmental Toxins

These days you need to be aware of protecting yourself from environmental toxins. Environmental toxins are toxins that may be in your drinking water, in what you eat, in the air you breathe, or they enter your body through your skin when you swim in contaminated water or walk on a sandy, wet beach.

In the following blog I will address some of these issues and how we can defend ourselves against toxins.

The youngest and most vulnerable

Toxins are particularly bad for infants and premature babies. Notably, the reasons for this are the following ones: their kidney function (tubular secretion) is only 20% to 30% of that of an adult; the cytochrome P-450 enzyme system in the liver, one of the toxin eliminators is slowed down to only 25% to 50% of the adult activity and glucuronidation in the liver, another detoxification process, reaches adult levels only at the age of 3 years.

Function of liver and kidneys

It is important to realize that the kidneys and the liver are limiting the removal of toxins by way of urine and bile in the newborn. Stomach acidity in a premature has a pH of 4.7, in a full-term newborn 2.3–3.6 and in an adult 1.4–2.0. This is important to note as a lack of stomach acid increases susceptibility of newborns and infants to gastrointestinal infections and cause diarrhea. Percutaneous absorption in newborns is much higher than in adults, which makes them very susceptible to absorbing toxins through the skin (Ref.1).

Diabetes from environmental toxins

Environmental toxins can cause insulin resistance and type 2 diabetes.

Bisphenol A (BPA) is used to make polycarbonate and epoxy resins and is found primarily in food and beverage containers. People all around the world had exposure to BPA  since 1957 and as a result 90% of US residents have detectable levels of BPA in their urine. Ref.2 explains that the higher the urine concentration of BPA, the higher the risk is for developing diabetes.

Persistent organic pollutants are another source of concern: pesticides and herbicides, dioxins, polychlorinated biphenyls, hexachlorobenzene, and hexachlorocyclohexane have all been found in humans. Several investigators have shown that virtually all of the risk in obese patients to develop diabetes comes from the fat-soluble persistent organic pollutants (Ref.2).

Inorganic arsenic

Inorganic arsenic is another pollutant from soil and rock, which finds its way into the drinking water. About 8% of the public water system of the US exceeds 10 mcg/L for drinking water, which is the safe limit for drinking water by the US Environmental Protection Agency’s standard. Anything above those levels is considered toxic.Ref.2 describes that people who ingest inorganic arsenic will excrete it in the urine; the highest group with arsenic in their urine had a risk of 3.58-fold to develop diabetes when compared to the lowest group. Curiously enough organic arsenic that is found in fish and shellfish is excreted in the urine unchanged and does not cause diabetes. Overall this indicates to me that nobody should consume or cook with contaminated water that contains inorganic arsenic. Reverse osmosis filters will protect you from this risk.

Protecting Yourself From Environmental Toxins

Protecting Yourself From Environmental Toxins

Other toxins around the house

Volatile organic compounds are often contained in carpets, but also in laser and inkjet printers. They are part of everyone’s life as this link shows. Physicians reported varied symptoms like irritation of eyes, nose or throat, breathing problems, headaches, loss of coordination, damage to the liver, kidneys and the brain after exposure to volatile organic compounds. Researchers noted that long-term exposure can cause cancer in animals and there is suspicion  that it causes cancer in humans as well.

Air fresheners and cleaning solutions that contain ethylene-based glycol ethers and terpenes were the subject of a study that examined concentrations in the air and interaction with ozone that can also be released by some cleaners.

Fumes of chemicals can cause lung cancer

As this link shows the investigators concluded that with exposure to high enough concentrations and long enough exposures to these fumes lung cancer can be caused in cleaning personnel. They recommended to use cleaning solutions only in diluted form and to air out the premises well after cleaning. Another component of many air fresheners and cleaning chemicals is paradichlorobenzene, the same chemical that is contained in mothballs.

There have been problems with flame retardants: polybrominated diphenyl ethers, which are cancer producing; the US outlawed them in 2004, but older mattresses, upholstery, television, computer casings and circuit boards may still contain them.

Lead and mercury poisoning, and radioactive pollutants

Lead in paints was outlawed since 1978, so manufacturers have not used lead in paints anymore. Paint from buildings older than that still may contain lead. There have been serious lead poisonings in children who were gnawing on items painted with lead containing paint. Lead causes problems with your central nervous system, brain, blood cells and kidneys. Just last year a news story about lead found in fashion jewelry surfaced warning about cheap fashion jewelry from China. Lead from these items can lead to absorption through the skin and cause lead poisoning. Because of the apparent lack of regulations in China I do not put anything into my mouth or on my skin, if it originates from China.

Mercury contamination of the environment

Mercury from tuna and other predator fish: It is sad that there is pollution in oceans to the point where it has become unsafe to eat predator fish. In predator fish there is an accumulation of mercury through the food chain.

How did things develop this way? Back 100 years and more ago gold panning and the purification process of gold caused mercury to enter into rivers and allow mercury to end up in the oceans where it has since accumulated; it just sits there as it has nowhere to go.

Coal burning (yes, there is mercury in coal) also contributed to this by smoke emission from smoke stacks containing mercury vapors. Subsequently the pollution from the air returns to earth as rain pollution and drained through the river system into the oceans.

Monomethylmercury poisoning

It is monomethylmercury that accumulates in the tissue of humans. This affects many organs, such as the brain, kidneys, lungs, and skin. It causes various symptoms like red cheeks, fingers, and toes; there can be bleeding from the mouth and ears; it can cause rapid heartbeats, high blood pressure, intense sweating, loss of hair, teeth, and nails. It also can cause blindness, loss of hearing, impaired memory, and lack of coordination, disturbed speech and birth defects. You may think all mercury comes from the outside. However, silver amalgam fillings in your teeth could also be the source of mercury poisoning. It is a good idea to replace amalgam/mercury fillings with ceramic fillings.

Other marine pollution

There are many forms of other marine pollution as this link shows.

One particular concerning aspect is pollution with radioactive materials as the Fukushima disaster in Japan has shown. Following the catastrophe on March 11, 2011 radioactive material leaked into the ocean, which is described here. Dr. John Apsley II pointed out that with the explosions in Fukushima there were also several releases of radioactive pollution into the stratosphere. This pollution has subsequently traveled around the globe and has come down as radioactive rain. He has made it his ambition to help people minimize radiation exposure from nuclear accidents such as Fukushima.

Protecting yourself from toxins

Having said that pollution and toxins are problems that we are living with, how can we protect ourselves from all of that?

1. Avoid as many unsafe chemicals around you as you can. This includes checking ingredients in hair care and body care products, toothpaste, hair dyes, cosmetics, mouthwashes and underarm deodorants.  I have written a blog about toxins in the bathroom and what you should watch for.

2. I would recommend you switch from a standard food to organic food. It has become unsafe to eat non-organic meats, leafy vegetables, vegetables and fruit. There are too many residues of herbicides and pesticides contained also in meat, not only in vegetables and fruit. Washing will not remove these substances, even though some merchants may tell you otherwise. Buyer beware!

Detoxification

3. Detoxification methods are available and I have reviewed them in this blog. Briefly, to remove lead and mercury you need to follow a formal intravenous chelation protocol.  Depending on how many heavy metal toxins you have on board, you may need only a few treatments. At the most you may require up to 20. Here is a more conservative website stating that it would be safe to have silver amalgam fillings. I think that gold and ceramic fillings are much safer.

4. Genetically modified food is another danger as I have summarized in this blog. This is another reason why I like to stick to organic food. There is evidence that GMO food causes autoimmune diseases, infertility and chronic inflammation that can eventually lead to cancer. It may take decades to prove this, but I am not willing to be a human guinea pig.

Remove toxins from your home

5. I have mentioned in a prior blog that we live in a toxic world. You need to carefully look at your home and remove toxins. You need to assess your drinking water. A water analysis can tell you how good the water in your home is and whether there are concerns about inorganic arsenic. Usually places that sell filter systems can advise you in that regard. Your drinking water should either be pure water bottles or else reverse osmosis water from a filter system in your house.

6.Vitamins and supplements support your cell integrity and have anti-inflammatory and antioxidant effects that protect you from toxins. I discussed this in detail in my NetHealthBook under nutrition. For instance vitamin D3 in doses of 5000 IU or more and CoQ-10 are powerful anti-inflammatories and CoQ-10 is also an antioxidant and preserves mitochondrial function. High fish oil supplements (3 to 6 Grams per day) have anti-inflammatory effects and protect your cell membrane integrity. With these overlapping qualities of vitamins and supplements your body will be in a much stronger position to defend itself against the negative effects of toxins. When you take multivitamins, this translates into telomere lengthening of 5.1%. This converts into a survival advantage of 9.8 years over a lifetime). Ref. 4 explains this in more detail.

Exposure to radioactive substances

7. Exposure to radioactive substances is a scary thought, but this is becoming more and more a reality, at least for those who live close to disaster areas such as the Fukushima site in Japan or the Chernobyl site in the Ukraine. But according to Dr. Apsley II low dose radiation that we have already received in the US and in Canada following the Fukushima disaster is equally disastrous (Ref.3). Many of the vitamins and supplements I have mentioned are also cell and mitochondria protective and will help with DNA repair following radiation damage, but you must avoid sugar and other refined carbs and starches to reduce the oxidative effect on cells and on LDL cholesterol to prevent premature aging and cell death. Ref. 3 contains a lot more detail about this and explains what specific supplements you can take to detoxify your system. This will remove radioactive elements that function as free radicals in your body. There are specific antidotes for radioactive iodine-129 and iodine-131, radioactive cesium-137 and others.

Conclusion

Many people shrug their shoulders when they hear that pollution has an effect on their lives. They feel that they are powerless and cannot do anything about this. The truth is far from this! Above I mentioned seven points that you can follow to counter toxins. On top of that you can get politically active and urge your government representative to create a nuclear free zone in your area. Ref. 3 contains compelling evidence why this is so important not only for us now, but for future generations and the future of mankind.

Accountability of quality of food and beverages

We need to hold those who provide us with food and beverages accountable for the quality of these. Shrugging it off is not good enough. Get involved. Buy organic food. Avoid the section in the grocery store where they sell sugar and high carb foods. It’s good for your own health, but it will collectively change the mentality of the grocery store owners where you shop. Suddenly they notice that they are now left with the comfort foods that were big sellers in the past. This new trend will result in cheaper prices for healthy foods and more availability of organic food.

References

1. Shannon: Haddad and Winchester’s Clinical Management of Poisoning and Drug Overdose, 4th ed. © 2007 Saunders. Chapter 18:“Toxicologic Issues in the Neonate”.

2. Rakel: Integrative Medicine, 3rd ed. © 2012 Saunders. Chapter 31: “Insulin Resistance and the Metabolic Syndrome”.

3. Dr. John W. Apsley II : “Fukushima Meltdown & Modern Radiation: Protecting Ourselves and Our Future Generations” © 2011. Temet Nosce Publications, Sammamish, WA 98075

4. Xu, Qun, Parks, C.G., DeRoo, L.A., Cawthon, R.M., Sandler, D.P. and Chen, H. Multivitamin use and telomere length in women. American Journal of Clinical Nutrition 89 (April 2009):1857-63. Full text (PDF): http://ajcn.nutrition.org/content/89/6/1857.full?sid=9aab0e13-b4d2-42ad-b44c-15cffc6771c3

Last edited March 8, 2014

Feb
08
2014

Sugar As A Cause Of Cancer

It has been known for a long time that cancer cells can survive without the ordinary aerobic pathways of energy production. They can get energy from a metabolic pathway, which bypasses normal cell metabolism (aerobic glycolysis). But many attempts of designing a cancer therapy to exploit this difference have so far been unsuccessful.

This Mayo Clinic website even explains that it would be a myth that cancer would grow better with sugar. The following pieces of research question this myth.

Sugar makes cancer grow faster (activates oncogenes) in fruit flies

In this study from the Icahn School of Medicine at Mount Sinai in New York City fruit flies were used as an animal model. You may ask, why fruit flies; we are not fruit flies, we are humans! As incredible as it sounds, on a cellular level our cell metabolism and the cell metabolism of fruit flies is identical. But the generation time of fruit flies is much shorter and results can be seen in days and weeks. To achieve the same in human trials would take months and years. Also, researchers could breed a strain of fruit flies that was susceptible to develop tumors. When they were fed sugar, the fruit flies developed insulin resistance within a short time. This model was chosen by the researchers as it is known for some time that in humans insulin resistance from diabetes, obesity, and other metabolic diseases leads to a higher risk of developing breast cancer, liver cancer, colon cancer and pancreatic cancer. The researchers wanted to sort out what the metabolic advantage of the cancer cells was under these conditions.

The researchers found that the sugar in the diet activated silent cancer causing genes (called “oncogenes)” in the fruit flies that in turn helped to promote insulin resistance and the development of tumors. Because of the insulin resistance sugar could not enter into the normal body cells, but the tumor was using up all of the sugar allowing the tumor cells to multiply at a rapid rate. The end result was that the sugar from the diet fed the cancer cells directly making them grow faster. Interestingly, when these flies that had developed tumors on a high sugar diet were switched to a high protein/low sugar diet, the tumors stopped growing and were contained.

In this fruit fly example the researchers were subsequently able to block cancer cell growth by special cancer suppressing drugs (acarbose, pyrvinium and an experimental drug AD81), which were given in combination. 90% of the flies given the triple-drug treatment survived to adulthood while control flies not treated with this regimen all died of their tumors.

Although this model was only done in fruit flies and one could question whether or not this was relevant to what is happening in human cancer patients, the following piece of research puts this fear to rest.

Sugar As A Cause Of Cancer

Sugar As A Cause Of Cancer

Human breast cancer cell study in vitro

In January 2014 the American Society for Clinical Investigation published a collaborative study between the Lawrence Berkeley National Laboratory, Berkeley, California, CA and the Hokkaido University Graduate School of Medicine, Japan, which used human breast cells in tissue culture showing that sugar could cause breast cancer.

The original papers of this US/Japanese research team are quite technical and I do not expect you to understand this link where it is published. I posted it for those who want in depth information. The researchers used a simple tissue culture model where they could observe tumor growth in cell cultures under the microscope using a gel where the breast tissue samples were placed side by side with normal breast cells that served as controls. The cell cultures of both normal cells and malignant cells were obtained from the same reduction mammoplasty tissue samples. This way the cell cultures mimicked a situation as close to the reality of what is going on in a woman’s body when breast cancer develops.

The normal breast epithelial cells were seen in culture to get organized as a roundish cell formation (an acinus formation) while the cancer cells were growing as irregular cell clumps. This visual effect was reproducible and is depicted in the paper. With high sugar concentrations in the growth medium breast cancer cells multiplied at a faster rate, not so the normal cells. But some normal cells underwent a transformation into abnormal and cancerous cell types. On the other hand, when sugar concentrations were severely restricted, morphological changes took place where cancer cells slowed down their growth or stagnated while some of them even changed into the normal cell formation (acinus formation). Using various known oncogene stabilizers the investigators could show that the same effect was noted as with the low sugar concentration in the growth medium.

The investigators tested whether other cell lines of breast cancer would show similar results as to the effects of sugar feeding or restriction. They were able to show that high sugar feeding activated cancer cells, no matter where the cancer cell lines originated. The authors discussed that metformin, which is known to control the metabolism in diabetic patients and lowers blood sugar levels, has also been shown to calm down growth of cancer (due to stopping oncogene stimulation), which improves the survival rates of many different cancer types in diabetic patients; it also reduces the risk of developing cancer in those who are taking metformin.

Other investigators have shown in mouse experiments that an impressive lowering of cancer rates could be achieved with low carb diets.

Human evidence for cancer causation and cancer prevention

Several clinical studies seem to indicate that there is a higher cancer rate in diabetics where insulin resistance can lead to activation of cancer producing genes (called oncogenes) and cause various cancers. In this link colorectal cancer and pancreatic cancer are discussed in relationship to diabetes and insulin resistance. High glycemic foods (sugar, starchy foods) were associated with breast cancer, colorectal cancer and endometrial cancer. The majority of trials showed this association although not all. The more obese patients were, the more pronounced the insulin resistance was and the more the relationship to these cancers became apparent. A diet that is high in starchy foods like potatoes, rice and bread is causing pancreatic cancer as was shown by researchers at the Dana-Faber Cancer Institute, Brigham and Women’s Hospital and Harvard School of Public Health. High glycemic diets have shown to cause colorectal cancer, diabetes and being overweight. The Standard North American Diet (SAD) is a pathway to many chronic illnesses due its high load in refined carbohydrates. Ironically the abbreviation for it is “SAD”, which in my opinion reflects adequately its sad influence on health and well being. We know now that sugar and starchy foods lead to insulin overproduction, which in turn causes the metabolic syndrome (also known as “insulin resistance”). This causes the immune system to weaken and fat to be deposited as visceral fat in the stomach area. Visceral fat is metabolically very active as it secretes cytokines like tumor necrosis factor alpha (TNF alpha), COX-2 enzymes and others. Insulin and growth factors from the visceral fat gang up together with the elevated blood sugar, which activates tumor-producing genes (oncogenes) to cause cancer.

While cancer rates are higher in patients with insulin resistance, they were lower in patients who did have normal insulin levels. It is important to concentrate your efforts on normalizing weight, which will normalize insulin sensibility and avoid the development of cancer. Sugar avoidance and avoidance of cereals and starchy foods will help you achieve this goal.

Conclusion

Although the idea that sugar could cause cancer has been around since 1924 (Dr. Warburg), it has taken up to now to be proven in animals and humans.

The purpose of this blog was to show how there is a connection between the consumption of sugar and starchy foods and various cancers in man. Animal experiments are useful in suggesting these connections, but many clinical trials including the Women’s Health Initiative have shown that these findings are also true in humans. It is insulin resistance due to sugar and starch overconsumption that is causing cancer.

We are now in a position to know why people who consume a low carb diet, develop less cancer than people who consume a high carb diet. I have followed such a low carb diet (also known as low-glycemic index food diet) since 2001 and find it easy to follow. However, I do not dispute that it takes some discipline to change the old way of eating to the new one. The benefits are definitely worth it: you are feeling well now and you are staying well as you age.

More information about hyperinsulinism that can cause breast cancer: http://nethealthbook.com/cancer-overview/breast-cancer/causes-breast-cancer/

Last edited Nov. 7, 2014

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Dec
28
2013

Airplane Food And Airport Food, A Personal Travel Experience

Travelling for pleasure is usually something we eagerly anticipate: it can associate with a long wished for vacation, meeting family and friends, enjoying a different environment, in short: there is a bit of adventure attached to it.

Getting something to eat while you are in transit, however, can be a different story. Let me share a recent experience that my wife and I had on a transcontinental flight.

We had to get up shortly after 4 AM, and knowing that we would be in transit till later that evening we decided to prepare an early breakfast. As we usually do, we packed some plastic bags with travel snacks and stashed them away into our back packs: walnuts, almonds, apples, some cheese, some hard boiled eggs and a chocolate bar (70 % cocoa) for an indulgent dessert. It felt a bit unusual to sit down to a vegetable omelet, enjoy some berries and nuts and fix a cup of Americano at 5 in the morning, but we got over the early hour and enjoyed our breakfast. It was a good start to cope with a three-hour time switch that awaited us at the end of the trip.

After checking in at the airport we were greeted with the pleasant news, that our seat arrangement had been upgraded: we would travel first class, as they could not accommodate us in economy. To complete the sense of unexpected luxury, a full breakfast would be included. We did not expect any gourmet fare, but it was welcome news. After some time the flight attendants started to serve the meal. The choices were a cereal bowl or a scrambled egg skillet southwestern style for breakfast. My readers know already that I do not hold the breakfast cereal in high esteem. Cereal has the undesirable effect of sending blood sugar levels to unhealthy highs and as a result causing insulin spikes, so it is not a prudent choice in the first place. We asked for the scrambled eggs, cautiously enquiring: ‘What is in it?”

Airplane Food And Airport Food, A Personal Travel Experience

Airplane Food And Airport Food, A Personal Travel Experience

We were informed that it would be scrambled eggs with some black beans, green and red peppers, ham, onion and some cheese. It sounded really good, and we felt like a glutton having eaten a substantial breakfast at home and now getting some more! It turned out to be a bit different. The meal arrived. It was a flat skillet dish, which consisted of a thick layer of potato cubes held together by a yellow substance, which could not really be described as scrambled eggs. About half a dozen cubes of peppers were identifiable along with a few black beans. I started mining for onions and ham and tried to dig out the egg. It was virtually impossible! The amount of egg that I could retrieve was not more than 1 level tablespoon, and there were a few tiny specks of ham. My wife had the same experience. Needless to say, the skillets were almost full of potatoes, when we sent them back. The flight attendant came through one more time and offered a basket of croissants and buns to complete the breakfast, which we politely refused. As you see, we did not have any need to feel guilty about ingesting a second breakfast onboard, as this meal was simply unsuitable for anybody who was seeking balance in nutrition. To make it short: it is almost exclusively overfeeding the consumer with a load of dense carbohydrates (potatoes, croissants and buns), neglects a sensible amount of protein, and omits any healthy fat source. Out of sheer curiosity I flicked through the pages of an in-flight magazine that listed the foods that could be purchased on board for lunch. The results were not inspiring. There was an assortment of snack foods: potato chips, pretzels, super-size chocolate chip cookies, a candy bar that I had met before on TV and beef jerky. The meal selection featured three types of sandwiches: ham and cheese, brie and turkey breast, and a “loaded” super Italian affair with salami, which looked like a guarantee to a case of indigestion. The cheese plate was sold out and the fresh fruit plate was gone too. Sorry, no luck! As a matter of fact we were lucky and so were all the other passengers who came prepared with a stash of travel foods. When we got hungry towards noon we dug out our travel snacks, drank some water and were quite satisfied.

On our return trip, we traveled economy class (no upgrade to first class food or first class seats this time). It was another lengthy trip coast to coast, and as there were two lengthy layovers, the day was even longer. We arrived at one international airport at the East coast by lunchtime. This time we decided to get a meal at one of the numerous eating establishments. After all, just recently news articles had praised airport restaurants having embraced many healthy food choices. So this would not be airplane food but REAL food! We had some time to walk around and explore, and it turned out, that we certainly needed it! We salivated at the sight of a choice of mahi-mahi with a mixed salad at one café. Cautiously we wondered whether this would be grilled fish. No, we were told, this would be breaded and deep-fried! And it would not be offered in any other way. Too bad, this was not really what we wanted! An Asian food outlet offered a buffet-style assortment of food. It did look very good, and we loved the chicken and vegetable choice or the beef and broccoli with mushroom dish. It did look fresh and appetizing. Often Asian foods can contain MSG. We wanted to make sure that this substance would not be in the food at this place. Sorry, we were told, all the meats and vegetables did contain MSG! Monosodium glutamate is not a harmless flavor enhancer. It belongs into the group of excitotoxins. The substance can destroy brain cells. It also has the potential to give you a nasty headache, especially if larger quantities are used. We were looking for food minus a headache, so we walked away once again and looked for more. An Italian bistro offered the usual suspects: piles of pasta and pizza! And there was a bakery with towering-high tortes, cinnamon buns, and muffins. It was overfeeding of the already carbo-holic individual and under nourishing the traveller. Sad!

After this expedition through the terminal we did finally find a meal that would sustain us until the evening. It was a pre-packaged Thai salad. It was certainly nothing fancy, but it contained a large amount of lettuce and other salad vegetables, offered a small but appropriate amount of cooked shredded real chicken, not some processed salty fake meat, and a small container of salad dressing on the side. It was enough to feel pleasantly full without feeling stuffed and good enough to keep us going till the evening.

Yes, we really wanted a touch of luxury for dessert! We thought of the duty free shop and envisioned a square or two of sinfully dark chocolate. Actually, this is not sinful at all! Have a piece of chocolate with over 70 % cocoa content or even 85%. It is not bitter, but an explosion of flavor on your taste buds, and it happens to be a source of anti-oxidants and bioflavonoids. It lowers high blood pressure and gobbles up free radicals, and as a result it can protect you from heart disease. One word of caution: use moderate amounts! Two or three squares only, not more, please!

And there was chocolate at the duty-free shop, lots of it! There were praline selections in large varieties, and there were Lindt and Ghirardelli chocolate bars, two well-known brands! We rejoiced…but too early! There were six packs featuring extra-creamy, sea-salt, caramel, chocolate and chili. As we studied the labels it was very obvious, that this was not at all what we were looking for! One bar in six was of excellent quality with a high cocoa percentage. The rest was a “gourmet mix”, all of them with low cocoa percentage and high sugar content, which really means it was useless. Were we willing to waste our money on half a dozen chocolate bars of which just one single bar was the merchandise we wanted? The answer was no! And of course, the package could only be sold this way; sorry, no choice! After leaving the duty free store with all its high-class brands behind, we found a humble news and magazine outlet. It had nice, entertaining reads to shorten the next leg of our journey. And-what a surprise! There was a stack of chocolates by an unknown European manufacturer with an 85 % cocoa content. Lucky us! An interesting magazine and dessert too! Bon voyage!

Conclusion

We do not think that we are the only health conscious persons on the planet. We hope that someone in charge in any airport or in an airline catering company smells a business opportunity. We are not demanding. We just prefer healthy foods and it would be great to find a meal choice with whole foods such as greens, vegetables, wild salmon, organic chicken, or grass-fed antibiotic-free beef. There is no need for anything elaborate. It’s really back to the basics! Even a mixed salad with a healthy protein portion would fit in very well. It is time that not just a few high class chefs around the world take notice of the new changes of a healthy diet that I summarized in this blog recently: “Buying Into High Carb, Low Fat Myth Makes You Sick”. In case you want to read more, I am in the process of publishing a book, which also contains 7 days of healthy menus at the end of it. It will be published early in 2014 through Amazon.com and is entitled: “A Survivor’s Guide To Successful Aging” (addendum Nov.7, 2014: It has been published March 31, 2014).

Last edited Nov. 7, 2014

Dec
07
2013

Slow Down Aging And Prevent Disabilities

You have seen it many times before: a man or a woman retires at age 65; for a while you see them around at social functions; then they are not seen any more and they return in a wheel chair only to die prematurely. You ask yourself: what can I do better to avoid this death trap?

There are several aspects to this equation: first, we would like to slow down the aging process. Part of this is to retain our physical functioning. In the following I am discussing the ingredients that are necessary to achieve the goal of aging in dignity, but avoiding disability.

It starts with a healthy mind set

You need to be optimistic and have a mindset of believing in yourself that you can do it. With a negative attitude, you will manage to find something to complain about, no matter how perfect the day has been. Negative thinking is rampant, and depression tends to be higher in the older population. If you suffer from depression or you had negative events such as accidents or abuse in the past, it is important to do some house cleaning. Do not be hesitant seeking professional help and counseling from a health professional to help you build up your self-esteem.

Regular exercise is important

A regular exercise program helps you to get your day organized. If you think that you are too busy to find the time to exercise, you are sacrificing your wellness and in fact you sabotage your health. It’s time to rethink your lifestyle! The reason you need exercise is to set the automatic pilot on staying healthy and active. If you are accustomed to sitting down in front of the computer or television set for hours, your muscles do not get the exercise they need. Fast-forward several decades and you will be one of those who rely on walkers, wheel chairs and assisted living establishments. Without training your muscles you are more prone to falls and injuries. Your balance organ is not getting the impulses it needs on an ongoing basis to prevent you from falls later in life. People in their 80’s are often stable up to the point where they trip and fall. I have seen many patients like this arrive in an ambulance where I was doing my shift as the emergency physician in a community hospital. When I summarize the fate of all of the people in their 80’s who had falls and broke their hips over the years, 50% of them made it through the surgery and went back home (often with a walker or in a wheel chair) or ended up in a nursing home; the other 50% died from complications of the surgery, often from heart attacks during the surgery or from clots in their pelvic veins or in the leg veins that dislodged and turned into pulmonary emboli. A fracture and in particular a hip fracture in your 80’s is a serious, potentially deadly accident. So, you need strong muscles and joints and you need strong bones. All of this comes free to you from years of regular exercise in your 60’s and 70’s.

Slow Down Aging And Prevent Disabilities

Slow Down Aging And Prevent Disabilities

You guessed right: good nutrition is important!

Eat right and your body will function right. This is where a lot of people are sent on the wrong path due to clever advertising from the Agro Industry, Big Pharma, the American Dietetic Association and the United States Department Of Agriculture. So they preach that wheat and wheat products are good for you, but the lab tests show that it induces hyperinsulinemia and leads to diabetes. The genetic changes of wheat (“accomplished” through forced chemical hybridization in the 1970’s) are responsible for the metabolically very active wheat belly (accumulation of visceral fat) that Ref. 1 has described in detail. But others have researched this topic as well. Ref. 2 for instance confirms that gliadin, the glue in wheat, which allows dough to stick and makes it easy to create bread, bagels and pasta, is responsible for neurological issues like numbness of fingers and feet (peripheral neuropathy), balance problems and cognitive decline all the way to Alzheimer’s disease. If you continue to eat wheat and wheat products (all contained in conveniently packaged “processed” foods), you may very well find that your balance and muscle control will deteriorate by the time you are in your eighties. This condition is not new: one of the lecturers I listened to at McMaster University in Hamilton, Ontario in 1977 referred to those unfortunate individuals who were severely disabled as the “tea and toasters”. The tea in this case was probably the lesser evil, but the wheat induced malabsorption and malnutrition was a reality already in the mid and late 1970’s.

However, if you start eating organic foods to avoid the chemicals and estrogen-like xenoestrogens from pesticides, and you cut out sugar, high-density carbs and wheat products, you will no longer have problems with weight control and you will maintain your muscle, brain and nerve function. This is not what you learn from the regular agencies mentioned at the beginning of this paragraph, but Ref. 1 and 2 will fill you in on the details. Essentially, I follow a Mediterranean diet without sugar, starchy foods and wheat or wheat products. Ref. 2 stressed the importance of enough saturated and healthy fat (omega-3 fatty acid rich oils) in a balanced diet consisting of 20% protein and low carbs. No specific numbers were given regarding the %-age of fat. I would say that a limit of about 25 to 35% for fat would be reasonable except for the Inuit who are used to a fat content in their diet of 80%. The new thinking is that healthy fats are good for your brain and heart. Healthy fats are omega-3 fatty acids (EPA and DHA) derived from fish oil as they are very protective (anti-inflammatory) oils, so is olive oil and coconut oil. These latter two are anti-inflammatory monounsaturated fatty acids. Keep in mind that you want to change the ratio of omega-3 to omega-6 fatty acids (the ratio in this link is cited as omega-6 to omega-3) more in the direction of omega-3 fatty acids, so that the ratio will be between 1:1 and 1:3. Most Americans are exposed to ratios of 1:8 to 1:16 (too many omega-6 fatty acids in fast food and processed foods), which leads to inflammation of the arteries as well. Omega-6 fatty acids, found in safflower oil, sun flower oil, grape seed oil and canola oil are bad for you when not balanced by enough omega-3’s (flax seed oil and fish oil) as they lead to inflammation through the arachidonic acid system in the body. It may be a surprise to you that saturated fats are OK: animal fat like butter, lard, cream, ghee (clarified butter), and other animal fats provided they come from clean (not antibiotic or bovine growth hormone treated) animals. Buy organic and buy organic meats as well such as grass fed beef and bison, chicken and turkey.

Here is an example of what a day would look like nutritionally in terms of a breakfast, lunch and dinner (recipes by Christina Schilling):

Breakfast:  Great Greens Omelet

(2 servings)

1 tablespoon olive oil or coconut oil

3 chopped green onions

3 cups spinach leaves or a mix of greens: kale, spinach, Swiss chard

1 red pepper cut into strips

3 eggs and 3 egg whites

2 tablespoons grated Parmigiano

In non-stick pan sauté green onion, greens and pepper strips in oil, stir eggs and egg whites and pour over the vegetables, sprinkle with Parmigiano. Cook on medium heat, till the egg mixture has started to set. Turn over and briefly let cook. Remove from pan, divide into two portions and sprinkle with a bit of salt (optional). Serve with salsa and guacamole.

Lunch: Oriental Salad

(2 portions)

1 small Sui choy cabbage (Napa cabbage)

2 cups mung bean sprouts

1 small daikon radish, shredded to yield 1 cup

1 red pepper, cut into thin slices

3 green onions, chopped

1 medium sized carrot, cut into matchstick size pieces

1 can sliced water chestnuts, rinsed.

Dressing: 2 tablespoons sesame oil,

2 tablespoons rice vinegar,(light balsamic vinegar works too)

1-tablespoon tamari soy sauce

1 tablespoon Thai sweet chilli sauce

1-teaspoon fresh grated ginger

3 tablespoons chopped fresh cilantro

Prepare all vegetables and put into salad bowl. Stir all dressing ingredients together and pour over vegetable mix. Stir gently, cover and refrigerate. This salad can be consumed immediately or kept refrigerted for a day. To complete the salad with a protein portion add your choice of 6 oz. cooked shrimp or the same quantity of cubed or sliced grilled chicken.

Dinner:  Florentine Chicken

(2 servings)

1 large boneless chicken breast

1 tablespoon of chopped fresh basil-alternatively use 1 teaspoon dried basil.

1 tablespoon grated Parmigiano

4 thin slices prosciutto

1 tablespoon olive oil

2 tomatoes- cut into halves

3 chopped green onions

2 cups baby spinach leaves

pinch of salt

Spread chicken breast flat and top it with the basil, Parmigiano and prosciutto slices. Fold into half an hold the stuffed chicken breast together at the edges with a toothpick or two. Heat olive oil in frying pan, add onion and tomato slices and put the chicken breast on top. Put lid on the pan, and cook at medium heat till the chicken is cooked through. If you test with a fork, the juices will be clear. Remove vegetables and chicken from pan, put on serving plate and keep warm. Remove toothpicks from meat, and cut chicken breast into two portions. Put spinach into pan and let the leaves wilt at medium heat (cover with lid). Put spinach on the side of the chicken and tomatoes, and sprinkle with a bit of salt.

Dessert after dinner: Berry Sorbet

(2 servings)

2 cups of deep frozen berries (strawberries, blueberries or a berry mix, no sugar added)

¾ cup of organic yogourt or goat’s milk yogurt

a few drops of liquid stevia or small amount of powdered stevia-to taste.

Put into blender and process till smooth. You will have to open the blender jar to stir the contents in between. Serve with a dollop of whipped cream,  if desired.

What about the “slow down” of menopause and andropause?

It is a fact that as we age, our hormone glands do not produce as much hormones as when we were in our 20’s and 30’s. But if you find a health care provider who is interested in anti-aging medicine (there are about 26,000 physicians, chiropractors and naturopaths who are members in the A4M), your hormones can be measured accurately from saliva and blood tests. This will tell whether you are hypothyroid, deficient in sex hormones and whether you should be supplemented with the missing hormones in adequate doses through bio-identical hormones. For instance, women are often deficient in progesterone in menopause and men deficient in testosterone. Treatment needs persistence and patience, as it often takes months for the patient to feel better and up to 2 years, to find the exact balance for you where the hormones are re-balanced and your symptoms of tiredness, insomnia, hot flushes etc. disappear. All our body cells have hormone receptors that require stimulation for the cells to function normally. Your health professional needs to pay attention to this and not just treat your symptoms symptomatically. When your hormones are in balance and you take a few supplements, your bones will be strong (no osteoporosis), your brain will be clear, your hearing perfect, and your balance great. You will be much less likely in your eighties to fall and break a bone and your mind will be clear and sharp.

Stress management

As the baby boomers age, they need to be aware of the stress in their lives. You may have been accustomed to having lots of energy when you were in your child rearing years or in your active professional career. Often we do not even notice that there may be stress in our lives. But your adrenal glands know. This is really a subpart of what I said of hormones: they need to be in balance. But cortisol, which is produced in your adrenal glands, is different from the menopause/andropause hormones. Corticotrophin-releasing hormone (CRH) from the hypothalamus and adrenocorticotrophin hormone (ACTH) from the pituitary gland are the rulers of the adrenal glands. And it is how you handle stress when you are in your 40’s, 50’s and 60’s which will determine whether you come down with adrenal fatigue, various degrees of adrenal insufficiency or not. Ref. 3 is a whole book that deals with this topic. Here I like to mention only that the best test to diagnose adrenal problems is a four-point saliva hormone test for cortisol. You connect the four points and get a curve where the cortisol level is expressed as a function of time. If this curve is below the lower normal range, which the laboratory provides for you, you need to be managed by a knowledgeable health care professional in order to build up the reserves of your adrenal glands. Yoga, meditation, deep prayer, self-hypnosis and enough regular sleep are all proven methods to overcome any stress related issues. Sometimes more effort is needed to rebuild the adrenals by specific herbs or porcine adrenal gland cortex extracts. Your health care provider can tell you more regarding this.

Useful supplements

1. On March 17, 2013 I wrote in a blog about prevention of osteoporosis the following summary:

“The best combination is 1000 mg (or 1200 mg as per National Osteoporosis Foundation recommendation) of calcium per day together with 400 to 800 IU of vitamin D3 (for cancer prevention you may want to take 4000 IU to 5000 IU of vitamin D3 per day instead monitored by a 25-hydroxyvitamin D blood level test through your physician) and 100 micrograms of vitamin K2 (also called MK-7). In the age group above 50 missing hormones such as bioidentical testosterone in men and bioidentical progesterone/estrogen combinations in women should be given as well. This works best, if you also watch your weight, cut down your alcohol consumption to a minimum (or better cut alcohol out altogether), exercise regularly (this builds up bone and muscle strength) and stick to a balanced diet resembling a Mediterranean or zone type diet (low-glycemic,  low fat, wheat free and no sugar).” I would add in view of Ref. 1 and 2 that “low fat” should now be replaced by “balanced fat diet”. With this I mean that nuts, almonds, olive oil, unsalted butter are allowed within reason. Lately there have been new insights that some cholesterol is needed for normal hormone production. What needs to be cut out are omega-6 fats and trans fats.

2. Omega-3-fatty acid supplements from molecularly distilled fish oil at a good dosage (3 to 6 capsules a day) will prevent chronic inflammation that often causes arthritis. Chicken cartilage (UC-II) from the health food store will desensitize your system in case you have rheumatoid arthritis or osteoarthritis. This will prevent crippling arthritic disease down the road.

3. Mitochondrial aging (the mitochondria are the energy packages in each body cell) is slowed down by the two supplements ubiquinol (=Co-Q-10, take 400 mg per day) and 20 mg of PQQ (=Pyrroloquinoline quinone). Co-Q-10 repairs DNA damage to your mitochondria and PQQ stimulates your healthy mitochondria to multiply. Between the two supplements you will have more energy.

4. Vitamin C 1000 to 2000 mg per day and a multivitamin supplement help to support the rest of your metabolism. Some may want to add PS (Phosphatylserine) 100 to 200 mg per day, which works together with vitamin D3 for Alzheimer’s prevention.

Conclusion

By now you noticed that nothing comes from ignoring the fact that we are aging. We need to pay attention to our body functions and think about what we can do to make us stronger. In the end we are our own caregivers. When we are in our eighties, we should still be active and our brains should function with a lot more experience than in our past. Our bones will be strong and our balance should prevent us from falling. I do not want to use assisted living and I do not like the confinement of a wheel chair. In the meantime I am going to carry on dancing.

More information on:

1. Fitness: http://nethealthbook.com/health-nutrition-and-fitness/fitness/

2. Nutrition: http://nethealthbook.com/health-nutrition-and-fitness/nutrition/

3. Vitamins, minerals and supplements: http://nethealthbook.com/health-nutrition-and-fitness/nutrition/vitamins-minerals-supplements/

References

1. William Davis, MD: “Wheat Belly. Lose the Wheat, Lose the Weight, and Find Your Path Back to Health”. HarperCollins Publishers LTD., Toronto, Canada, 2011.

2. David Perlmutter, MD: “Grain Brain. The Surprising Truth About Wheat, Carbs, And Sugar-Your Brain’s Silent Killers.” Little, Brown and Company, New York, 2013.

3. James L. Wilson, ND, DC, PhD: “Adrenal Fatigue, the 21sty Century Stress Syndrome – what is it and how you can recover”; Second printing 2002 by Smart Publications, Petaluma, Ca, USA

Last edited Nov. 7, 2014